Ulcerative Colitis (Pediatric) Clinical Trials

A listing of Ulcerative Colitis (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 171 clinical trials
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A3921210 OVATION  

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US patients with prior TNFi failure or intolerance will be enrolled. Outside of the US, TNFi naïve and TNFi experienced patients will be enrolled.All eligible participants …

pediatric ulcerative colitis
cancer
budesonide
azathioprine
prednisone
  • 0 views
  • 18 Jun, 2021
  • 3 locations
Diet Intervention Treatment for Active Ulcerative Colitis

The purpose of this study is to determine if a sustainable non-elemental diet can be used as a probiotic tool to alter the dysbiotic microbiome found in individuals with ulcerative colitis and thereby decrease disease activity.

medical therapy
  • 0 views
  • 25 May, 2021
  • 1 location
Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative Colitis

Evaluation of the microbiota modulation away from inflammation associated microbiota profile Bacteroides2 (Bact2) Evaluation of the microbiota modulation potential of statins in Bact2- enterotyped, healthy volunteers and ulcerative colitis patients. Evaluation of the effect of microbiota modulation on disease activity in ulcerative colitis patients. Evaluation of reduced inflammatory parameters of …

remission
microbiota
  • 0 views
  • 21 May, 2021
  • 2 locations
Clinical Study of Cord Blood Mononuclear Cells on Treatment of Hormone-resistant or Hormone-dependent Ulcerative Colitis

This study conducted a systematic clinical observation of the clinical efficacy of UCB-MNCs in the treatment of hormone-resistant or hormone-dependent ulcerative colitis, in order to observe its clinical safety and efficacy.

prednisone
adalimumab
azathioprine
  • 0 views
  • 22 May, 2021
  • 1 location
A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The reason for this study is to determine if the study drug LY3471851 is safe and effective in adult participants with active ulcerative colitis (UC). The study will last about 52 weeks.

cancer
tumour necrosis
immunomodulators
azathioprine
endoscopy
  • 0 views
  • 20 Jun, 2021
  • 130 locations
A Study of Ustekinumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis (UC)

The purpose of this study is to evaluate: a) the efficacy of ustekinumab dosing in inducing clinical remission, b) safety profile of ustekinumab, and c) ustekinumab exposure (pharmacokinetics [PK]) in pediatric participants with moderately to severely active UC.

endoscopy
remission
  • 0 views
  • 20 Jun, 2021
  • 57 locations
A Multicenter Randomized Double-Blind Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2. The objective of Sub-Study 2 is to …

remission
  • 604 views
  • 21 Jun, 2021
  • 773 locations
Study of OSE-127 vs Placebo in Patients With Moderate to Severe Active Ulcerative Colitis

This is a phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-group study in patients with moderate to severe active ulcerative colitis.

vedolizumab
hematochezia
monoclonal antibodies
endoscopy
tumor necrosis factor
  • 0 views
  • 21 Jun, 2021
  • 55 locations
Phase 2 Dose-finding IMU-838 for Ulcerative Colitis

This is a phase 2, multicenter, randomized, double-blind, placebo-controlled, dose-finding study to evaluate the efficacy and safety of IMU-838 for induction and maintenance therapy with an option for open-label treatment extension in moderate-to-severe ulcerative colitis (CALDOSE-1).

tumour necrosis
immunomodulators
vedolizumab
tumor necrosis factor alpha
adalimumab
  • 220 views
  • 11 Jun, 2021
  • 190 locations
A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this study is to evaluate the efficacy and safety of mirikizumab as maintenance therapy in participants who completed prior 12-week induction study AMAN (NCT03518086).

endoscopy
mirikizumab
  • 386 views
  • 20 Jun, 2021
  • 904 locations