Glioblastoma multiforme Clinical Trials

A listing of Glioblastoma multiforme medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 52 clinical trials
A Study of BLZ945 Single Agent or BLZ945 in Combination With PDR001 in Advanced Solid Tumors

> Dose escalation will be guided by a Bayesian logistic regression model with overdose control. Once MTD/ RP2D is declared, glioblastoma patients will be enrolled in the phase II part to further assess

  • 0 views
  • 01 Aug, 2021
  • 18 locations
Combined Treatment of Camrelizumab and Bevacizumab for Adult Patients With Recurrent Glioblastoma (GBM)

This study is intend to explore the efficacy and safety of combined treatment of camrelizumab and bevacizumab in adult patients with recurrent glioblastoma.

  • 0 views
  • 17 Jul, 2021
  • 1 location
[18F]Fluciclovine in Post-treatment Glioblastoma ( Axumin )

Subjects with histologically proven glioblastoma (GBM) who are suspected to have progression and are candidates for a surgical resection according to standard of care may be eligible for this

chemoradiotherapy
karnofsky performance status
  • 1 views
  • 25 Jul, 2021
  • 1 location
Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma

The purpose of this study is to determine the safety and tolerability of Regorafenib in patients with recurrent or progressive glioblastoma (GBM) who have progressed on bevacizumab. Regorafenib

nitrosoureas
cancer
carcinoma in situ
neutrophil count
bevacizumab
  • 0 views
  • 01 Aug, 2021
  • 2 locations
Supramarginal Resection in Glioblastoma

Gliomas are the most common malignant brain tumor. Glioblastoma, WHO grade IV astrocytoma, is the most common subtype and unfortunately also the most aggressive subtype with median survival in

complete resection
supratentorial glioblastoma multiforme
brain tumor
tumor cells
gross total resection
  • 0 views
  • 23 Jul, 2021
  • 19 locations
2-OHOA With RT and TMZ for Adults With Glioblastoma

The proposed Phase IIB/III randomized, double-blind, placebo-controlled trial in subjects with newly diagnosed primary glioblastoma multiforme (ndGBM) aims to compare the efficacy and safety of

renal function test
tamoxifen
temozolomide
neutrophil count
malignant glioma
  • 12 views
  • 25 Jul, 2021
  • 14 locations
Pivotal Randomized Open-label Study of Optune (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM

To test the effectiveness and safety of Optune given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM patients, compared to radiation therapy and

complete resection
tumor treating fields therapy
cancer
tumor progression
corticosteroids
  • 0 views
  • 31 Jul, 2021
  • 155 locations
A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy

alone in patients with recurrent or progressive glioblastoma multiforme (GBM) following treatment with first line therapy consisting of surgery and radiation with or without chemotherapy.

tumor treating fields therapy
methylated
astrocytoma
aptt
bevacizumab
  • 1520 views
  • 31 Jul, 2021
  • 73 locations
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

This is a phase 1 study of an anti-CD40 monoclonal antibody (2141-V11) in combination with D2C7-IT for patients with recurrent World Health Organization (WHO) grade III or IV malignant glioma at the Preston Robert Tisch Brain Tumor Center (PRTBTC) at Duke.

recurrent malignant glioma
brain tumor
malignant glioma
  • 0 views
  • 31 Jul, 2021
  • 1 location
Lymphocyte Depletion and Change in Lymphocyte Functionality

Lymphocytes are a type of white blood cell (WBC) found in the participant's blood. During radiation treatment, moving blood is exposed to radiation. This may cause a decrease in the amount of lymphocytes. A researcher at UVA has created a system to predict and reduce the immune cell reduction following …

  • 0 views
  • 29 Jul, 2021
  • 1 location