Colon cancer; rectal cancer Clinical Trials

A listing of Colon cancer; rectal cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 592 clinical trials
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

The purpose of this study is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer of the colon or rectum that has spread.

metastatic colorectal cancer
colon cancer
nivolumab
  • 278 views
  • 28 Jun, 2022
  • 36 locations
Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

From the patients' perspective, the most formidable part of the colonoscopy experience is the process of bowel cleansing. A poorly tolerated bowel preparation regimen often leads to incompletion of scheduled colonoscopies which in turn undermines the effectiveness of colonoscopy, increases cost, and decreases patient satisfaction. The current standard bowel preparation …

bowel preparation
  • 63 views
  • 28 Feb, 2022
  • 1 location
Adjuvant Low Dose Aspirin in Colorectal Cancer (ALASCCA)

ALASCCA is a randomized, parallel group, double blind, multicenter, placebo-controlled, biomarker-based study of adjuvant treatment with low dose aspirin in patients with colorectal cancer. Hypothesis is that patients diagnosed with colorectal cancer and somatic mutations in PI3K pathway can significantly improve survival if treated with low dose aspirin.

rectal carcinoma
aspirin
  • 29 views
  • 03 May, 2022
  • 32 locations
Aspirin for Prevention of Postsurgical Recurrence and Metastasis in Asian Colorectal Cancer Patients: a Multi-center Randomized Trial

Background: Evidence of high quality has suggested that acetylsalicylic acid (ASA)/aspirin effectively reduces colorectal adenoma incidence and recurrence rate, and several randomized controlled trials (RCTs) strongly indicate its potential to prevent colorectal cancer (CRC) initiation and progression and to decrease cancer-related mortality. However the role of aspirin supplied as an …

adjuvant therapy
platelet count
metastasis
anticoagulants
aspirin
  • 13 views
  • 21 Jan, 2021
  • 1 location
Scaling Colorectal Cancer Screening Through Outreach, Referral, and Engagement (SCORE): A State-Level Program to Reduce Colorectal Cancer Burden in Vulnerable Populations (SCORE)

This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75. We are implementing this study in two age groups, 45-49 years and 50-75 years.

fecal immunochemical test
Accepts healthy volunteers
blood test
adenoma
  • 0 views
  • 18 Sep, 2022
  • 1 location
Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis (CANWATCH)

Adjuvant chemotherapy was unnecessary in pathological stage Ⅱ colorectal cancer following initial treatment of surgery without high risk factors of recurrences. The treatment efficacy of adjuvant chemotherapy for pT1-3N0M0 colorectal cancer following preoperational chemotherapy or chemoradiotherapy remains unclear. Part of clinical local advanced colorectal cancer(cTxN1-2M0), which turn out to be …

adjuvant chemotherapy
adenocarcinoma
cancer
chemotherapy regimen
  • 0 views
  • 21 Mar, 2022
  • 1 location
Anesthesia and Cancer Study: Colon Cancer

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

anesthesia
sevoflurane
tiva
propofol
cancer surgery
  • 394 views
  • 12 May, 2022
  • 2 locations
Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis

2 Year randomised, double-blind, placebo-controlled, parallel group study to determine the safety and efficacy of EPA-FFA gastro resistant capsules in FAP.

rectal anastomosis
eicosapentaenoic acid
aspirin
colectomy
  • 5 views
  • 10 Feb, 2022
  • 11 locations
Treatment Strategies in Colorectal Cancer Patients With Initially Unresectable Liver-only Metastases (CAIRO5)

Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy. However, the optimal neoadjuvant induction regimen has not been defined, and no consensus exist on criteria for resectability. In this study colorectal cancer patients with initially unresectable liver-only metastases, as prospectively …

panitumumab
neutrophil count
systemic therapy
primary tumor
folfiri regimen
  • 249 views
  • 07 Apr, 2022
  • 50 locations
Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia (CAN)

The purpose of this study is to determine whether anesthesia maintained with propofol results in better one- and five-year-survival than anesthesia maintained with sevoflurane.

immunostimulant
anesthesia
sevoflurane
general anesthesia
propofol
  • 30 views
  • 05 Jun, 2022
  • 14 locations