Colon cancer; rectal cancer Clinical Trials

A listing of Colon cancer; rectal cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 615 clinical trials
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What if there were a simpler way to find colorectal cancer?

ECLIPSE is being done to find out if a simple blood test can find early signs of colorectal cancer. Colorectal cancer is the #2 cause of death among adults with cancer, but it doesn’t have to be.  If found early, it’s one of the most preventable and treatable cancers.  NOW …

  • 352 views
  • 23 Mar, 2022
  • 1 location
Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

This study was a randomized, controled, multicenter, phase II clinical study evaluating the efficacy and safety of fruquintinib as a maintenance therapy following first-line treatment for metastatic colorectal cancer. This study will include the patients with confirmed unresectable metastatic left-sided colon cancer with RAS mutation or right-sided colon cancer who …

  • 0 views
  • 15 Nov, 2021
  • 1 location
The Efficacy and Safety of Modified XELOX(mXELOX) Plus Cetuximab vs FOLFOX Plus Cetuximab in RAS and BRAF WT mCRC Pts

This is an open label, multicenter, randomized study in Chinese patients with RAS and BRAF wild-type mCRC. Participants were randomly assigned to cetuximab + FOLFOX (group A) and cetuximab + modified XELOX[mXELOX] (group B). All patients in groups A and B will be treated until progression of disease(PD), death, intolerable …

  • 0 views
  • 19 Oct, 2021
  • 1 location
A Patient-centered Intervention Using Technology to Reduce Colorectal Cancer Disparities in Primary Care

The purpose of this proposal is to test the efficacy of a patient-centered, tailored message intervention delivered via virtual technology for increasing colorectal cancer (CRC) screening within guidelines among racial/ethnic minority and rural patients. This protocol focuses on the clinical portion of grant NCI 1RCA207689-01A1

Accepts healthy volunteers
  • 7 views
  • 15 Mar, 2022
  • 1 location
Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation

Preoperative radiation and chemotherapy is the standard treatment for local advanced rectal cancer. The addition of oxaliplatin to capecitabine combined with radiotherapy does not improve local control and long-term survival. Most importantly,chemoradiotherapy significantly increased surgical complication and poor long-term quality of life .In the absence of effective measures of predicting …

rectal surgery
chemoradiotherapy
pelvic mri
leucovorin
total mesorectal excision
  • 4 views
  • 14 Feb, 2022
Pelvic Drain After Rectal Resection for Mid-low Rectal Cancer

This RCT aims at assessing the effects of a pelvic drain after total mesorectal excision for mid-low rectal cancer on the rates of pelvic sepsis and anastomotic leaks.

total mesorectal excision
proctectomy
  • 0 views
  • 25 Jan, 2021
Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone (REPCA)

The purpose of the study is to determine if short-term outcomes of rectal resections after full bowel preparation (mechanical bowel preparation plus oral antibiotics) are superior to rectal resections with only mechanical bowel preparation.

proctectomy
adenocarcinoma
  • 0 views
  • 05 May, 2022
  • 1 location
Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure

oxaliplatin
folfox regimen
capecitabine
xelox
adenocarcinoma
  • 0 views
  • 10 Nov, 2021
  • 1 location
The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection

A randomized controlled clinical trial to compare the short and long outcomes of low anterior resection for middle-low rectal cancer with or without pelvic peritonization.

low anterior resection
adenocarcinoma of rectum
adenocarcinoma
  • 0 views
  • 25 Jan, 2021
  • 1 location
Low or High Ligation of the IMA With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery

Laparoscopy colon surgery is accepted worldwide in the recent years. But there is still argument on the effect of laparoscopy rectal surgery. Laparoscopy has advantages on showing the inferior mesenteric artery (IMA), protection of autonomic nerve, low rectal anastomosis, and total mesorectum excision. However, debate on the level of IMA …

rectal surgery
general anesthesia
rectal anastomosis
metastasis
fluorouracil
  • 0 views
  • 25 Feb, 2022
  • 1 location