Cytomegalovirus Infections Clinical Trials

A listing of Cytomegalovirus Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 125 clinical trials
A Study of Modified mRNA Vaccines in Healthy Adults

The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.

Accepts healthy volunteers
  • 8 views
  • 17 Jun, 2022
  • 3 locations
Randomized, Controlled Trial to Evaluate the Anti-inflammatory Efficacy of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive ART and Its Effect on Chronic Inflammation, HIV Persistence, and Other Clinical Outcomes (ELICIT)

This is an open-label, controlled study, conducted at US sites to evaluate the anti-inflammatory effectiveness of the study drug letermovir in adults with HIV and asymptomatic cytomegalovirus

hysterectomy
atazanavir
hiv test
hiv-1 rna measurement
immunodeficiency
  • 0 views
  • 14 Sep, 2022
  • 1 location
CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Blood Cancer Undergoing Donor Stem Cell Transplant

This phase II trial studies how well multi-peptide CMV-modified vaccinia Ankara (CMV-MVA Triplex) vaccination of stem cell donors works in preventing cytomegalovirus (CMV) viremia in

Accepts healthy volunteers
lymphoma
hepatitis
myelogenous leukemia
myeloid leukemia
  • 50 views
  • 04 Mar, 2022
  • 1 location
  • 0 views
  • 20 Apr, 2022
  • 15 locations
Adoptive Cord Blood Immunotherapy for EBV, CMV, BKV and Adenovirus Reactivation/Infection or Prophylaxis

This Phase I-II dose-finding trial to determine the optimal dose of intravenous (IV) injection dose of donor-derived cytotoxic T lymphocytes (CTLs) specific for CMV, EBV, BKV and Adenovirus. A

absolute neutrophil count
cmv infection
nephropathy
  • 63 views
  • 05 Mar, 2022
  • 2 locations
TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT. (TETRAVI)

-Epstein Barr virus (EBV), cytomegalovirus (CMV), adenovirus (AdV), Human polyomavirus type I (BKV), and human polyomavirus type II (JCV)- that has persisted or recurred despite standard therapy.

cmv infection
methylprednisolone
  • 1 views
  • 25 Mar, 2022
  • 2 locations
Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

This phase II trial studies how well letermovir works for the prevention of cytomegalovirus reactivation in patients with hematological malignancies treated with alemtuzumab. Patients receiving

  • 0 views
  • 15 Mar, 2021
  • 1 location
Impact of Anti-cytomegalovirus Treatment in the Management of Relapsing Ulcerative Colitis Requiring Vedolizumab Therapy (CYTOVEDO)

> CytoMegaloVirus (CMV) reactivation has been associated with resistance to steroid and to several lines of immunosuppressive therapy. Antiviral therapy was proven to decrease the tissue viral load and to restore

  • 0 views
  • 22 Apr, 2022
  • 6 locations
A Phase II Randomized, Placebo-Controlled, Multicenter Trial to Evaluate the Protective Function of CMV-MVA Triplex Vaccine in Adult Recipients of Haploidentical Hematopoietic Stem Cell Transplant

This phase II trial studies how well Triplex vaccine works in preventing cytomegalovirus (CMV) infection in patients undergoing a hematopoietic stem cell transplantation. CMV is a virus that may

immunosuppressant
ct scan
myeloid leukemia
beta human chorionic gonadotropin
cytomegalovirus infection
  • 13 views
  • 22 Sep, 2022
  • 1 location
RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.

In prior trials of CMV RNA-pulsed dendritic cell vaccines, there has been a narrow window between surgery and initiation of chemoradiation to enroll patients and perform leukapheresis (to obtain

sargramostim
beam radiation
neutrophil count
karnofsky performance status
platelet count
  • 0 views
  • 15 May, 2022
  • 1 location