Cytomegalovirus Infections Clinical Trials

A listing of Cytomegalovirus Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 124 clinical trials
Clinical Trial of Efficacy and Safety of the Combination of Reduced Duration Prophylaxis Followed by Immuno-guided Prophylaxis in Lung Transplant Recipients. (CYTOCOR)

To assess the efficacy of reduced duration prophylaxis followed by immuno-guided prophylaxis to prevent cytomegalovirus disease.

ganciclovir
valganciclovir
dhpg
  • 1 views
  • 17 Feb, 2022
  • 6 locations
A Phase 3, Open-Label, Single-Arm Study to Assess the Efficacy, Safety, and Pharmacokinetics of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Japanese Recipients of a Hematopoietic Stem Cell Transplant (HSCT) or Solid Organ Transplant (SOT)

The main aim of the study is to check if treatment with maribavir can protect Japanese people against Cytomegalovirus (CMV) infection, and to check side effect from the study treatment and how

  • 0 views
  • 16 Sep, 2022
  • 18 locations
A Phase 1/2, First-Time-in Human (FTiH), Randomized, Observer-blind, Placebo-controlled, Dose Escalation Study to Assess Safety, Reactogenicity and Immunogenicity of a Candidate Cytomegalovirus (CMV) Vaccine Comprising Recombinant Protein and Adjuvant When Administered Intramuscularly in Healthy Adults

The purpose of this study is to assess the safety, reactogenicity and immunogenicity of the candidate CMV recombinant protein subunit (CMVsu) vaccine consisting of a combination of glycoproteins

Accepts healthy volunteers
  • 43 views
  • 22 Sep, 2022
  • 14 locations
Multicenter Clinical Trial to Evaluate the Efficacy of a Preventive Strategy Against CMV Infection in Heart Transplant Patients Based on the Specific T Cells Response

This study evaluates the efficacy and safety of an individualized preventive strategy against CMV infection in CMV seropositive heart transplant patients based on the specific basal response of

ifn-g
  • 12 views
  • 28 Jan, 2021
  • 1 location
A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients

This study measures the tolerability of viral-specific T cells against Cytomegalovirus (CMV) in adult solid organ transplant (SOT) recipients. Participants are expected to be on study for 52

ganciclovir
valganciclovir
viral therapy
letermovir
kidney transplant
  • 2 views
  • 15 Feb, 2022
  • 1 location
PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (PRiME)

The primary goal of this prospective clinical trial is to evaluate the safety of PEP-CMV in patients with recurrent medulloblastoma and malignant glioma. Patients with histologically-proven

neutrophil count
brain mri
malignant glioma
chemoradiotherapy
MRI
  • 22 views
  • 19 Jun, 2022
  • 1 location
NAVA vs. CMV Crossover in Severe BPD

This prospective, unblinded, pilot randomized cross-over trial of 2 modes of mechanical ventilation will compare measures of pulmonary mechanics, respiratory gas exchange, and patient comfort between conventional flow triggered mechanical ventilation and neurally adjusted ventilatory assist (NAVA) among 20 prematurely born infants and young children receiving invasive respiratory support for …

  • 2 views
  • 29 Sep, 2021
  • 1 location
Viral Specific T-Lymphocytes to Treat Adenovirus, CMV and EBV

The primary purpose of this phase I/II study is to evaluate whether partially matched, ≥2/6 HLA-matched, viral specific T cells have efficacy against adenovirus, CMV, and EBV, in subjects who

prednisone
stem cell transplantation
solid organ transplant
organ transplantation
cancer
  • 6 views
  • 04 Oct, 2022
  • 1 location
CMV Specific T Cell Therapy After Allogeneic Stem Cell Transplantation.

refractory to antiviral treatments, or in some cases an adequate antiviral treatment is unavailable or too toxic. In this study, the investigators will target CMV, as refractory CMV infection and disease is

cell transplantation
ganciclovir
viral therapy
stem cell transplantation
antiviral drugs
  • 47 views
  • 24 Feb, 2022
  • 8 locations
A Study of Modified mRNA Vaccines in Healthy Adults

The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.

Accepts healthy volunteers
  • 8 views
  • 17 Jun, 2022
  • 3 locations