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Cytomegalovirus Infections Clinical Trials

A listing of Cytomegalovirus Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (58) clinical trials

A research study is evaluating an investigational Cytomegalovirus (CMV) vaccine in generally healthy women of childbearing potential.  

Phase N/A

A research study is evaluating an investigational Cytomegalovirus (CMV) vaccine in generally healthy women of childbearing potential.  

Phase N/A

What is the SOLSTICE study? The SOLSTICE study is a clinical research study designed to explore an investigational drug-maribavir-in stem cell transplant and solid organ transplant recipients whose CMV infections are not responding to current treatments. This investigational drug is given as an oral pill. The main goal of the ...

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

The purpose of this study is to characterize the PK ( Pharmacokinetics) of understudied drugs administered to children per standard of care as prescribed by their treating caregiver. This will be accomplished by the collection of biological samples during the time of drug administration per standard of care as prescribed ...

Phase N/A

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

Viral infections are normally controlled by T-cell immunity and so are an important cause of morbidity and mortality during the period of immune recovery after hematopoietic stem cell transplantation (HSCT).1 Risk for infection is impacted by the degree of tissue mismatch between donor and recipient and the immune status of ...

Phase

T Cell Therapy of Opportunistic Cytomegalovirus Infection

The primary objective of this study is to determine the feasibility of the treatment of opportunistic cytomegalovirus (CMV) infections after hematopoietic stem cell transplant (HSCT) with virus-specific, antigen-selected T-cells, selected using the CliniMACS prodigy system. Secondary Objective(s) To describe the safety profile of the infusion of CMV- specific, antigen selected ...

Phase N/A

Preemptive Therapy With CMV-specific T Cells Infusion to Prevent Refractory CMV Infection Post Transplantation

Acute lymphoblastic leukemia (ALL) patients enrolled into this clinical trial are standard risk patients diagnosed with acute leukemia or myelodysplastic syndrome (MDS) and received haploidentical blood and marrow transplantation. When patients develop acute graft versus host disease (aGVHD), CMVpp65-specific T cells will be generated and transferred to the aGVHD controlled ...

Phase

Cell-mediated Immunity for Prevention of CMV Disease

An open-label randomized controlled trial to adapt the duration of antiviral prophylaxis in D+/R- patients and in R+ patients receiving ATG according to the result of the T-Track CMV assay. Investigators will include kidney and liver transplant recipients. Patients will be randomized during the first month post transplant. In the ...

Phase N/A

Relevance of Gastric Aspirate in HCMV Detection

Human cytomegalovirus (CMV) is the leading cause of neonatal viral infection and can have a significant impact on the neurosensory development of newborns and especially premature infants. CMV infection can result from materno-fetal transmission during pregnancy (congenital infection) or postnatal transmission. The prevalence of congenital CMV infection in the newborn ...

Phase N/A

Evaluation of the Benefit of Antiviral Treatment With Valganciclovir on Congenital CMV Infection-related Deafness on Hearing and Balance

Congenital cytomegalovirus (CMV) infection is the leading cause of non-genetic neurosensory deafness and affects 0.5 to 1% of births. Twenty to thirty per cent of children will develop deafness, some of whom will progress gradually to profound bilateral deafness. No curative treatment is currently offered for this deterioration in hearing ...

Phase