Lymphocytic Leukemia, Chronic Clinical Trials

A listing of Lymphocytic Leukemia, Chronic medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 332 clinical trials
Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, combined with acalabrutinib for the treatment of adults with Diffuse Large B-Cell Lymphoma and Chronic Lymphocytic

b-cell lymphoma
btk inhibitor
leukemia
diffuse large b-cell lymphoma
large b-cell lymphoma
  • 0 views
  • 12 Aug, 2021
  • 8 locations
A Study of JNJ-64264681 in Participants With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia

The purpose of the study is to determine the recommended Phase 2 dose(s) (RP2D[s]) in B cell non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL) in Part 1 and to evaluate the

leukemia
hodgkin's disease
beta human chorionic gonadotrophin
lymphoid leukemia
lymphoma
  • 25 views
  • 16 Sep, 2021
  • 17 locations
Study to Assess the Efficacy and Safety of Ublituximab + Umbralisib With or Without Bendamustine and Umbralisib Alone in Patients With Previously Treated Non-Hodgkins Lymphoma

Unity NHL - A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + Umbralisib with or without Bendamustine and Umbralisib alone in Patients with Previously Treated Non-Hodgkin's Lymphoma

umbralisib
b-cell lymphoma
large b-cell lymphoma
btk inhibitor
stem cell transplantation
  • 12 views
  • 22 Sep, 2021
  • 204 locations
A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL

This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 in patients with CLL/SLL and NHL who have failed or are intolerant to standard of care.

b-cell small lymphocytic lymphoma
renal function
chronic lymphocytic leukemia refractory
anemia
btk inhibitor
  • 93 views
  • 22 Sep, 2021
  • 102 locations
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia

The trial is an open-label, multi-center satefy and efficacy trial of epcoritamab in relapsed/refractory chronic lymphocytic leukemia (R/R CLL). The trial consists of two parts, a dose

  • 0 views
  • 22 Jun, 2021
  • 19 locations
GEN3013 Trial in Patients With Relapsed Progressive or Refractory B-Cell Lymphoma

The trial is an open-label, multi-center safety trial of epcoritamab GEN3013 (DuoBody-CD3xCD20). The trial consists of two parts: a dose escalation part phase 1, first-in-human (FIH) and an expansion part phase 2a.

renal function
large b-cell lymphoma
high grade b-cell lymphoma
stem cell transplantation
monoclonal antibodies
  • 319 views
  • 08 Aug, 2021
  • 100 locations
Efficacy and Safety of MK-1026 in Participants With Hematologic Malignancies (MK-1026-003)

The purpose of this study is to evaluate the safety and efficacy of MK-1026 (formerly ARQ 531) in participants with hematologic malignancies of chronic lymphocytic leukemia (CLL)/ small

hepatitis b surface antigen
measurable disease
leukemia
kinase inhibitor
lymphoma
  • 2 views
  • 18 Sep, 2021
  • 14 locations
Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

This partially randomized clinical trial studies cholecalciferol in improving survival in patients with newly diagnosed cancer with vitamin D insufficiency. Vitamin D replacement may improve tumor response and survival and delay time to treatment in patients with cancer who are vitamin D insufficient.

cyclin d1
extranodal nk/t-cell lymphoma, nasal type
immunoglobulin
cyclophosphamide
angioimmunoblastic t-cell lymphoma
  • 87 views
  • 13 Apr, 2021
  • 2 locations
Study to Assess Safety Tolerability Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignancies

The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary antitumor activity of AZD4573 in subjects with relapsed or refractory haematological malignancies.

lymphocytic leukemia
chronic myelomonocytic leukemia
progressive disease
renal function
leukemia
  • 98 views
  • 03 Sep, 2021
  • 23 locations
Safety and Efficacy of ThisCART19 in Patients With Refractory or Relapsed B Cell Malignancies

This is a study to evaluate the safety and clinical activity of ThisCART19 (Allogeneic CAR-T targeting CD19) in patients with refractory or relapsed CD19 positive B cell malignancies.

  • 0 views
  • 27 Jan, 2021
  • 3 locations