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Hemodialysis Clinical Trials

A listing of Hemodialysis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (152) clinical trials

Expanded Hemodialysis Versus Online Hemodiafiltration

Hypothesis Our hypothesis is that HDx is noninferior to olHDF in the following parameters: Hemodynamic stability Nutritional and fluid status Removal of beta-2 microglobulin Objectives To evaluate each patient, through a prospective, randomized and cross-over study, the intradialytic hemodynamic behavior, fluid and nutritional status assessed by electrical bioimpedance and B2M ...

Phase N/A

The Benefit of Hemodialysis Plus Hemoperfusion on Mortality

In this HD/HPvsHD trial, we plan to enroll 1364 maintenance hemodialysis patients. Eleven medical centers in Shanghai Metropolitan area have explicitly expressed interest to participate. Participants will be randomized to receive hemodialysis plus hemoperfusion or hemodialysis alone at a 1:1 ratio after 1-month run-in period. In both arms, patients will ...

Phase N/A

Underlying Causes of Low Vitamin K Status in Hemodialysis Patients

Studies have reported a low vitamin K status in chronic kidney disease patients in hemodialysis linked to an increased risk of atherosclerosis and increased bleeding tendency. The overall aim of this study is to investigate the underlying causes of the reported low vitamin K status and to improve the patients' ...

Phase N/A

Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes

The objective of this study is to evaluate efficacy and safety outcomes following use of the Sirolimus-eluting Collagen Implant (SeCI) in subjects undergoing surgical creation of an AV fistula for vascular access (index procedure). Following successful creation of the AV fistula, the cohort randomized to the treatment group will receive ...


Hemodialysis in the Elderly (70yrs & Older)

This will be a prospective, single institution, parallel-group, single-blinded, randomized-controlled, two-arm, effectiveness study comparing autologous arteriovenous fistula versus hemodialysis access grafts in the elderly. The target sample size will include enrollment of 270 patients over a period of 5 years. The creation of an autologous arteriovenous fistula or placement of ...

Phase N/A

High-flux Hemodialysis Versus Hemodiafiltration for End-Stage Renal Disease

Hemodialysis using diffusion, ultrafiltration and convection principle to remove harmful substances in the blood and excessive water, is one of the most commonly replacement therapy. Hemodiafiltration is a combination of hemodialysis and hemofiltration with two modes of treatment advantages, both by diffusion and convection principle to remove harmful substances in ...

Phase N/A

Cost-effectiveness of Urgent-start Therapies Hemodialysis and Peritoneal Dialysis

Despite evidence of worse outcomes, initiation of renal replacement therapy by unplanned modalities in chronic kidney disease (CKD) patients is the reality in the practice for both hemodialysis and peritoneal dialysis. Unplanned therapy peritoneal dialysis (PD) is the initiation of the modality in less than 48 hours after implantation of ...

Phase N/A

ACCESS HD: Comparing Catheters to Fistulas in Elderly Patients Starting Hemodialysis

Purpose: This pilot RCT will help to address challenges related to patient recruitment, protocol adherence, safety, and data collection in the hemodialysis population. The primary outcome for this pilot RCT is feasibility, which will be measured by patient recruitment and protocol adherence. The secondary outcomes include feasibility-related outcomes, safety (which ...

Phase N/A

Twice Against Thrice-weekly Hemodialysis

Hemodialysis (HD) is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. This treatment that relies heavily on technology has undergone major modifications in the last five decades in order to improve patients' outcomes. Those changes that aimed at reducing the morbidity and mortality of patients ...

Phase N/A

Does Incremental Initiation of Haemodialysis Preserve Native Kidney Function?

This study is feasibility randomised controlled trial. 50 patients who have newly started on haemodialysis will be recruited into the study from 4 UK centres. Eligible patients will be approached prior to initiation of dialysis or after starting dialysis. The details of the study will be explained to them and ...

Phase N/A