Myasthenia Gravis generalised Clinical Trials

A listing of Myasthenia Gravis generalised medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 11 clinical trials
Myasthenia Gravis Inebilizumab Trial (MINT)

Randomized, double-blind, placebo-controlled, Phase 3, parallel-group study with optional open-label extension.

corticosteroids
anti-musk antibody
mycophenolate mofetil
immune globulin
azathioprine
  • 12 views
  • 15 Aug, 2023
  • 67 locations
Autologous T-Cells Expressing A Chimeric Antigen Receptor Directed To B-Cell Maturation Antigen (BCMA) In Patients With Generalized Myasthenia Gravis (MG)

This is a Phase Ib/IIa study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis

generalized myasthenia gravis
immunosuppressive agents
  • 0 views
  • 25 Oct, 2022
  • 7 locations
The Curative Effect of Extended Thymectomy Performed Through Subxiphoid-right VATS Approach With Elevation of Sternum

Extended thymectomy is the main treatment for thymoma and other anterior mediastinal diseases. Video-assisted thoracic surgery(VATS) plays an important role in the surgery of extended thymectomy. Now, VATS thymectomy through intercostal approach has been the commonly used minimally invasive surgical procedure for thymus surgery and is applied worldwide. But the …

thymus hyperplasia
thymoma
thymectomy
mediastinal diseases
anterior mediastinum
  • 22 views
  • 12 Feb, 2022
  • 5 locations
Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases

This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a stem cell transplant works in treating patients with autoimmune neurologic disease that did not respond to previous therapy. In autoimmune neurological diseases, the patient's own immune system 'attacks' …

vasculitis
variable number tandem repeat
stiff person syndrome
hematopoietic stem cell transplantation
gait ataxia
  • 221 views
  • 16 Sep, 2023
  • 3 locations
Clinical Prognosis and Progression of Myasthenia Gravis Patients

This study collects the clinical data of myasthenia gravis (MG) patients, assesses outcomes and adverse effects of different treatment regimens, and searches for risk factors of conversion to generalized MG.

pyridostigmine
plasma exchange
immunoglobulins
immunosuppressive agents
igiv
  • 0 views
  • 21 Feb, 2022
  • 1 location
The EXPLORE MG Registry for Myasthenia Gravis

The purpose of this study is to create a Yale University Department of Neurology Myasthenia Gravis (MG) registry that will be used for current and future research projects involving the study of Myasthenia Gravis.

  • 37 views
  • 03 Sep, 2023
  • 1 location
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures …

rare diseases
other disease
  • 4 views
  • 15 Jul, 2022
  • 2 locations
Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis

This study is designed to evaluate the effectiveness and safety of tacrolimus combined with low-dose prednisone in the management of myasthenia gravis patients, compared to tacrolimus as initial immune monotherapy.

  • 0 views
  • 07 Mar, 2021
  • 1 location
TheRapeutic Effect of Different immunosuppressAnts on Non-Thymoma Ocular Myasthenia Gravis: a Real-world Study (TREAT-OMG)

This study collects the clinical data of new-onset ocular myasthenia gravis (OMG) patients, assesses outcomes and adverse effects of different treatment options, and evaluate risk factors of conversion to generalized MG(GMG).

thymoma
pyridostigmine
single fiber emg
mycophenolate mofetil
immune globulin
  • 0 views
  • 04 Oct, 2022
  • 1 location
Registry of Participants With Generalized Myasthenia Gravis Treated With C5 Inhibition Therapies

This is a long-term, multicenter, observational registry of participants with generalized myasthenia gravis (gMG) who are treated with Alexion complement C5 inhibition therapies (C5IT) prior to enrollment.

generalized myasthenia gravis
  • 22 views
  • 12 May, 2022
  • 10 locations