Myasthenia Gravis generalised Clinical Trials

A listing of Myasthenia Gravis generalised medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 18 clinical trials
Myasthenia Gravis Inebilizumab Trial (MINT)

Randomized, double-blind, placebo-controlled, Phase 3, parallel-group study with optional open-label extension.

mycophenolate mofetil
anti-musk antibody
azathioprine
corticosteroids
immune globulin
  • 9 views
  • 22 Apr, 2022
  • 65 locations
Subcutaneous Immunoglobulin for Myasthenia Gravis

This is a prospective open-label, randomized, parallel arm clinical trial. The primary objective of the study is to evaluate the safety and efficacy of Cuvitru 20% subcutaneous immunoglobulin in patients with myasthenia gravis (MG). The secondary objective is to evaluate patient preferences and effects on quality of life when treating …

  • 4 views
  • 03 Feb, 2021
  • 1 location
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)

This is a Phase Ib/IIa study to evaluate the safety and preliminary efficacy of Descartes-08 CAR T-cells in patients with Generalized Myasthenia Gravis

generalized myasthenia gravis
immunosuppressive agents
  • 0 views
  • 24 Apr, 2022
  • 7 locations
Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Myasthenia Gravis

This is a phase II, single center, randomized, double-blind, placebo-controlled, study in patients with a diagnosis of anti-AchR antibody positive myasthenia gravis.

pyridostigmine
immune globulin
ondansetron
  • 11 views
  • 15 May, 2022
  • 1 location
The Curative Effect of Extended Thymectomy Performed Through Subxiphoid-right VATS Approach With Elevation of Sternum

Extended thymectomy is the main treatment for thymoma and other anterior mediastinal diseases. Video-assisted thoracic surgery(VATS) plays an important role in the surgery of extended thymectomy. Now, VATS thymectomy through intercostal approach has been the commonly used minimally invasive surgical procedure for thymus surgery and is applied worldwide. But the …

thymoma
vats
thymus hyperplasia
thymectomy
anterior mediastinum
  • 21 views
  • 12 Feb, 2022
  • 5 locations
Autologous Peripheral Blood Stem Cell Transplant for Neurologic Autoimmune Diseases

This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a peripheral blood stem cell transplant works in treating patients with autoimmune neurologic disease that did not respond to previous therapy. In autoimmune neurological diseases, the patient's own immune …

ataxia
neuromyelitis optica
carmustine
blood stem cell transplant
hematopoietic stem cell transplantation
  • 195 views
  • 14 May, 2022
  • 3 locations
Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

This clinical trial will evaluate two non-surgical devices designed to improve eye lid opening for patients with severe Blepharoptosis (incomplete opening of the eyelids).

mental state exam
brimonidine tartrate ophthalmic solution
  • 0 views
  • 01 Aug, 2021
  • 1 location
The EXPLORE MG Registry for Myasthenia Gravis

The purpose of this study is to create a Yale University Department of Neurology Myasthenia Gravis (MG) registry that will be used for current and future research projects involving the study of Myasthenia Gravis.

  • 32 views
  • 06 Feb, 2022
  • 1 location
Clinical Prognosis and Progression of Myasthenia Gravis Patients

This study collects the clinical data of myasthenia gravis (MG) patients, assesses outcomes and adverse effects of different treatment regimens, and searches for risk factors of conversion to generalized MG.

immunoglobulins
igiv
immune globulin
antibody test
pyridostigmine
  • 0 views
  • 21 Feb, 2022
  • 1 location
The Impact of Myasthenia Gravis in the Real World

An international, non-interventional, prospective, community recruited, longitudinal, lifestyle study which aims to collect Real-World Evidence (RWE) from people living with myasthenia gravis (MG) in order to map the disease's natural history, its burden on patients and their families, its treatment, as well as its medical, social and pharmacoeconomic impact.

  • 0 views
  • 21 Feb, 2022
  • 1 location