Anemia; Non-Small-Cell Lung Cancer Clinical Trials

A listing of Anemia; Non-Small-Cell Lung Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 21 clinical trials
Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia

Fludarabine-based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated donor in persons 0-70 years of age diagnosed with dyskeratosis congenita or severe aplastic anemia who have bone marrow failure characterized by a requirement for red blood cell and platelet transfusions. Three different preparative regimens …

fludarabine
aplastic anemia
pancytopenia
glomerular filtration rate
cyclophosphamide
  • 24 views
  • 24 Mar, 2022
  • 1 location
Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Background Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

aplastic anemia
platelet count
blood test
eltrombopag
neutrophil count
  • 115 views
  • 21 Apr, 2022
  • 1 location
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Dyskeratosis congenita is a disease that affects numerous parts of the body, most typically causing failure of the blood system. Lung disease, liver disease and cancer are other frequent causes of illness and death. Bone marrow transplantation (BMT) can cure the blood system but can make the lung and liver …

fludarabine
alemtuzumab
aplastic anemia
alkylating agents
telomerase rna
  • 46 views
  • 11 May, 2022
  • 16 locations
Haploidentical HCT for Severe Aplastic Anemia

This study is a prospective, single center phase II clinical trial in which patients with Severe Aplastic Anemia (SAA) ) will receive a haploidentical transplantation. The purpose of this study is to learn more about newer methods of transplanting blood forming cells donated by a family member that is not …

fludarabine
red blood cell transfusion
cyclophosphamide
ejection fraction
glomerular filtration rate
  • 5 views
  • 07 Oct, 2022
  • 1 location
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

Background Cord blood is blood that is taken from the umbilical cord and placenta of healthy newborns after childbirth. The cord blood collected from a baby is called a cord blood unit. Cord blood units are stored frozen in public cord blood banks. About 10,000 cord blood transplants have been …

cancer
cell transplantation
hematologic malignancy
  • 41 views
  • 19 Oct, 2022
  • 1 location
TPO-Mimetic Use in Children for Hematopoietic Failure

This is an open label, prospective Pilot interventional study will investigate the safety and efficacy of Romiplostim, thrombopoietin (TPO) mimetic, in children (ages: 0 to 21 years) with broad scope of bone marrow failure disorders including acquired and inherited conditions as a first line of therapy along with standard of …

aplastic anemia
platelet count
thrombopoietin receptor agonist
splenectomy
pancytopenia
  • 0 views
  • 07 Oct, 2022
  • 1 location
Umbilical Cord Blood Transplantation From Unrelated Donors

This study is a single-center, treatment protocol with 4 possible preparative regimens, designed to validate the process of umbilical cord blood stem cell transplantation at our institution.

severe combined immunodeficiency
leukemia
hodgkin's disease
blast crisis
anemia
  • 80 views
  • 12 Jul, 2022
  • 1 location
Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

This clinical trial studies the use of reduced intensity chemotherapy and radiation therapy before donor stem cell transplant in treating patients with hematologic malignancies. Giving low doses of chemotherapy, such as cyclophosphamide and fludarabine phosphate, before a donor stem cell transplant may help stop the growth of cancer cells. It …

donor lymphocyte infusion
refractory anemia with ringed sideroblasts
leukemia
hodgkin's disease
neoadjuvant therapy
  • 66 views
  • 29 Jun, 2022
  • 1 location
Anti-Viral Central Memory CD8 Veto Cells in Haploidentical Hematopoietic Stem Cell Transplantation

This phase I/II trial studies how well cytokine-treated veto cells work in treating patients with hematologic malignancies following stem cell transplant. Giving chemotherapy and total-body irradiation before a stem cell transplant helps stop the growth of cells in the bone marrow, including normal blood-forming cells (stem cells) and cancer cells. …

leukemia
hodgkin's disease
hematologic malignancy
anemia
gilbert's syndrome
  • 64 views
  • 24 Oct, 2022
  • 1 location
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study

Background A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these disorders. Pathogenic variant(s) in IBMFS genes are relevant to carcinogenesis in sporadic cancers. Patients with IBMFS who develop cancer differ in their genetic and/or environmental features from patients …

pancytopenia
synostosis
bone marrow failure disorders
anemia
fanconi's syndrome
  • 43 views
  • 24 Oct, 2022
  • 2 locations