Liver Transplantation Clinical Trials

A listing of Liver Transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 299 clinical trials
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis

cirrhosis requiring liver transplantation or resulting in death. The investigational drug, Obeticholic Acid (OCA) is a modified bile acid and FXR agonist that is derived from the primary human bile acid

investigational drug
liver transplant
ursodiol
obeticholic acid
cholangitis
  • 402 views
  • 27 May, 2021
  • 323 locations
Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines

Treatment with Tenofovir Alafenamide(TAF) in Chronic Hepatitis B (CHB) patients classified as beyond treatment indication of current international guidelines (e.g. aged more than 40 years old and 4 log HBV-DNA IU/mL < 8) is expected to bring improvement in long-term clinical outcomes. This expected result may expand the treatment indications …

estimated creatinine clearance
hepatitis b antigen
chronic hepatitis
hepatitis
tenofovir
  • 0 views
  • 25 Apr, 2021
  • 1 location
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery

This partially randomized phase II/III trial studies how well, in combination with surgery, cisplatin and combination chemotherapy works in treating children and young adults with hepatoblastoma or hepatocellular carcinoma. Drugs used in chemotherapy, such as cisplatin, doxorubicin, fluorouracil, vincristine sulfate, carboplatin, etoposide, irinotecan, sorafenib, gemcitabine and oxaliplatin, work in different …

cancer therapy
oxaliplatin
glomerular filtration rate
carcinoma
abdominal compartment syndrome
  • 178 views
  • 01 Aug, 2021
  • 138 locations
Study on the Optimal Strategy for Acute-on-chronic Liver Failure With Integrative Treatment

Background: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute deterioration in the setting of chronic liver disease associated with high short-term mortality. Currently, there is no specific treatment for patients with ACLF. Our previous results showed that Chinese herbal medicine (CHM) could reduce the mortality rate and the …

acute on chronic liver failure
hepatitis
liver disease
hepatic failure
cytokines
  • 4 views
  • 03 Feb, 2021
  • 15 locations
  • 0 views
  • 16 Apr, 2021
  • 1 location
Bacillus Clausii in Liver Transplantation

living donor liver transplantation surgery.

  • 0 views
  • 19 Sep, 2021
Liver Transplantation With Tregs at MGH

This is a single-center, prospective, open-label, non-randomized clinical trial exploring cellular therapy to facilitate immunosuppression withdrawal in liver transplant recipients.

hepatitis
liver disease
everolimus
tacrolimus
cyclophosphamide
  • 0 views
  • 26 Jan, 2021
Liver Transplantation With Tregs at UCSF

This is a single-center, prospective, open-label, non-randomized clinical trial exploring cellular therapy to facilitate immunosuppression withdrawal in liver transplant recipients.

hepatitis
everolimus
cyclophosphamide
immunosuppression
vaccination
  • 0 views
  • 31 Aug, 2021
  • 1 location
LIFT Intervention in Liver Transplant Candidates

Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is

  • 0 views
  • 18 Apr, 2021
  • 1 location
Thromboelastometry in Liver Transplantation

Thromboelastometry better assess coagulation than standard coagulation test in patients undergoing ortothopic liver transplantation. In a post-hoc analysis from a randomized study recently

blood products administration
liver transplant
coagulation test
clot
fibrinogen
  • 6 views
  • 23 Jan, 2021
  • 2 locations