Gall Bladder Disorders Clinical Trials

A listing of Gall Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 39 clinical trials
Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer

Considering that the poor prognosis of resected biliary tract cancer and negative impact on the survival outcomes of R1/R2 resection, neoadjuvant chemotherapy may improve R0 resection rates and the survival outcomes of patients with resectable biliary tract cancer. The addition of durvalumab to gemcitabine/cisplatin as neoadjuvant chemotherapy may improve the …

durvalumab
gemcitabine/cisplatin
biliary tract cancer
pet scan
malignant disease
  • 1 views
  • 02 Aug, 2021
  • 1 location
Chemothetapy FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

The purpose of this study is to evaluate the feasibility, efficacy and safety of FORFIRINOX in advanced or recurrent extrahepatic cholangiocarcinoma and gallbladder carcinoma.

  • 0 views
  • 22 Jan, 2021
  • 1 location
Molecularly Target Therapy With FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

The purpose of this study is to evaluate the feasibility, efficacy and safety of target therapy according to genomic and proteomic profiling combined with FORFIRINOX in advanced or recurrent extrahepatic cholangiocarcinoma and gallbladder carcinoma.

cholangiocarcinoma
tyrosine
extrahepatic cholangiocarcinoma
gallbladder carcinoma
mates
  • 15 views
  • 22 Jan, 2021
  • 1 location
Pembrolizumab in Biliary Tract Cancer

This is a single-arm, multi-centre, phase II study in biliary tract cancer (BTC) patients. The main objective is to detect an increase in progression-free survival rate at 6 months (according to RECIST version 1.1) from 60% in patients with BTC treated with standard chemotherapy (CT) approach to 75% when treated …

biliary tract carcinoma
drainage
renal function
symptom control
gemcitabine/cisplatin
  • 78 views
  • 25 Mar, 2021
  • 7 locations
Two-in-one Covered and Uncovered Metal Stent

Endoscopic placement of a self-expandable metal stent (SEMS) is the principle method for palliation of inoperable malignant distal biliary obstruction. However, none of bare, covered, and anti-reflux metal stent alone constantly demonstrated superiority over the others in the stent patency. To compensate for the limitations of each stent, a double …

metastasis
obstruction
reflux
biliary obstruction
  • 0 views
  • 31 Jul, 2021
  • 1 location
PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)

PLATON (Platform for Analyzing Targetable Mutations) is a prospective, multicentre, observational cohort study with biobanking. In a first approach PLATON's pilot-study assesses genomic profiling in gastrointestinal cancer therapy and the frequencies of targetable mutations including Tumor Mutational Burden (TMB) and Microsatellite Instability Status (MSI), performing Next-generation deep sequencing (NGS) using …

  • 0 views
  • 28 Jan, 2021
  • 3 locations
A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer.

absolute neutrophil count
platelet count
hepatitis b antigen
minor surgical procedures
fludarabine
  • 35 views
  • 30 Aug, 2021
  • 1 location
Behavioral Weight Loss Program for Cancer Survivors in Maryland

Behavioral Weight Loss for Overweight and Obese Cancer Survivors in Maryland: A Demonstration Project

tamoxifen
cancer
breast cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene fusion.

absolute neutrophil count
solid tumor
growth factor
platelet count
neutrophil count
  • 0 views
  • 09 Aug, 2021
  • 24 locations
SPY Fluorescence Imaging Systems and Indocyanine Green as a Tool for Developing Intelligent Peri-Operative Imaging

This is a prospective single arm, single center study estimating percentage of successful critical anatomy recognition in laparoscopic cholecystectomy surgeries using SPY fluorescence imaging and ICG to develop intelligent imaging tools (I-IT), with each surgery also providing a white light 360 degree images. The primary objective is to determine the …

cholecystectomy
indocyanine green
  • 0 views
  • 22 Aug, 2021
  • 1 location