Anemia; Non-Hodgkin’s Lymphoma Clinical Trials

A listing of Anemia; Non-Hodgkin’s Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients

The objective of this study is to evaluate the efficacy and safety of RBC transfusion for support of acute anemia in cardiovascular surgery patients based on the clinical outcome of renal impairment following transfusion of red blood cells (RBCs) treated with the INTERCEPT Blood System (IBS) for Red Blood Cells …

anemia
blood transfusion
red blood cell transfusion
  • 12 views
  • 04 Jun, 2021
  • 16 locations
Myocardial Ischemia and Transfusion

The purpose of this study is to compare two red blood cell transfusion strategies (liberal and restrictive) for patients who have had an acute myocardial infarction and are anemic.

ischemia
blood transfusion
acute myocardial infarction
stemi
red blood cell transfusion
  • 378 views
  • 13 Jun, 2021
  • 122 locations
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

The purpose of this Phase 3 study is to evaluate the efficacy and safety of Luspatercept compared with placebo in subjects with myeloproliferative neoplasm (MPN)-associated Myelofibrosis (MF) and anemia on concomitant Janus kinase 2 (JAK2) inhibitor therapy and who require red blood cell count (RBC) transfusions. The study is divided …

anemia
vasectomy
cancer
bilateral oophorectomy
  • 0 views
  • 14 Jun, 2021
  • 158 locations
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

The aim of this study to evaluate the safety and efficacy of a nonmyeloablative conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with sickle cell disease (SCD) who have a matched related major ABO-incompatible donor. The nonmyeloablative regimen will use alemtuzumab, total body irradiation (TBI) and …

transplant conditioning
stroke
cell transplantation
blood transfusion
conditioning regimen
  • 9 views
  • 03 Jun, 2021
  • 1 location
Study to Evaluate Efficacy and Safety of BGE-117 in the Treatment of Unexplained Anemia of Aging (UAA)

The primary objectives of this study to evaluate the safety, tolerability and efficacy of BGE-117 in the treatment of unexplained anemia in aging (UAA) in participants 65 years of age.

anemia
iron
transferrin saturation
vitamin b12
transferrin
  • 0 views
  • 13 Jun, 2021
  • 11 locations
TPO-Mimetic Use in Children for Hemotopoietic Failure

This is an open label, prospective Pilot interventional study will investigate the safety and efficacy of Romiplostim, thrombopoietin (TPO) mimetic, in children (ages: 0 to 21 years) with broad scope of bone marrow failure disorders including acquired and inherited conditions as a first line of therapy along with standard of …

thrombocytopenic purpura
anemia
cell transplantation
blood transfusion
reticulocyte count
  • 0 views
  • 13 Jun, 2021
  • 1 location
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Dyskeratosis congenita is a disease that affects numerous parts of the body, most typically causing failure of the blood system. Lung disease, liver disease and cancer are other frequent causes of illness and death. Bone marrow transplantation (BMT) can cure the blood system but can make the lung and liver …

hypocellular bone marrow
alkylating agents
hla-a
alemtuzumab
fanconi's anemia
  • 31 views
  • 03 Jun, 2021
  • 16 locations
To Assess the Safety and Tolerability of INCB000928 in Participants With Myelodysplastic Syndromes or Multiple Myeloma.

This Phase 1/2, open-label, dose-finding study is intended to evaluate the safety and tolerability, PK, PD, and efficacy of INCB000928 administered as monotherapy in participants with MDS or MM who are transfusion-dependent or present with symptomatic anemia.

anemia
carfilzomib
myelodysplastic syndromes
lenalidomide
bortezomib
  • 0 views
  • 13 Jun, 2021
  • 9 locations
Cord Blood Transplant With OTS for the Treatment of HIV Positive Hematologic Cancers

This phase II trial studies the side effects of a cord blood transplant using OTS and to see how well it works in treating patients with human immunodeficiency virus (HIV) positive hematologic (blood) cancers. After a cord blood transplant, the immune cells, including white blood cells, can take a while …

anemia
bone marrow failure
tumor cells
blast cells
HIV Vaccine
  • 0 views
  • 04 Jun, 2021
  • 5 locations
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for patients unable to receive further radiation). followed by a post-transplant graft-versus-host disease (GVHD) prophylaxis regimen of post-transplant cyclophosphamide (PTCy), tacrolimus (Tac), and mycophenolate …

cell transplantation
tacrolimus
busulfan
lymphoma
cancer chemotherapy
  • 58 views
  • 01 Jun, 2021
  • 1 location