Acute Myelogenous Leukemia (AML) Clinical Trials

A listing of Acute Myelogenous Leukemia (AML) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 185 clinical trials
Safety and Effectiveness of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Quizartinib is an experimental drug. It is not approved for regular use. It can only be used in medical research. Children or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or is not …

hematologic malignancy
flt3 internal tandem duplication
cancer
induction chemotherapy
methotrexate
  • 61 views
  • 07 Oct, 2022
  • 38 locations
Study Evaluating the Safety and Effectiveness Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia (AML) (ENHANCE-3)

acute myeloid leukemia (AML) who are ineligible for intensive chemotherapy.

carbon monoxide
venetoclax
ejection fraction
leukapheresis
azacitidine
  • 0 views
  • 07 Oct, 2022
  • 17 locations
A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia

myeloid leukemia (AML).

refractory acute myeloid leukemia (aml)
flt3 internal tandem duplication
venetoclax
azacitidine
hydroxyurea
  • 21 views
  • 07 Oct, 2022
  • 19 locations
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia (SCOPE-L)

outcomes in patients with acute myeloid leukemia (AML).

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Previously Untreated Patients With TP53 Mutant Acute Myeloid Leukemia (ENHANCE-2)

The primary objective of this study is to compare the efficacy of magrolimab + azacitidine versus venetoclax + azacitidine in adults with previously untreated TP53 mutant acute myeloid leukemia

gilbert's syndrome
TP53
leukapheresis
azacitidine
cytarabine
  • 1 views
  • 28 Oct, 2022
  • 71 locations
  • 0 views
  • 14 Oct, 2022
  • 75 locations
An Open-Label, Multi-Center, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420 as a Single Agent in Hematologic and Molecular Relapsed/Refractory Acute Myeloid Leukemia

to participants with Acute Myeloid Leukemia (AML) in order to determine the maximum tolerated dose (MTD) and/or recommended Phase II dose (RP2D).

cyclosporine
graft versus host disease
blast cells
tacrolimus
  • 0 views
  • 22 Oct, 2022
  • 24 locations
Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

The trial is open to all patients with a diagnosis of acute promyelocytic leukemia (APL) who are PCR-positive for the PML-RAR transcript and less than 18 years of age.

  • 0 views
  • 04 Oct, 2022
  • 29 locations
An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)

with Acute Myeloid Leukemia (AML) and AML secondary to myeloproliferative neoplasms (MPN). Participants must be relapsed/refractory (having failed prior therapy) and will be assigned to receive

decitabine
refractory acute myeloid leukemia (aml)
cytarabine
cancer
  • 2 views
  • 04 Oct, 2022
  • 55 locations
A Phase Ib, Multi-arm, Open-label, Study of HDM201 in Combination With MBG453 or Venetoclax in Adult Subjects With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)

This is a phase 1b, multi-arm, open-label study of HDM201 in combination with MBG453 or venetoclax in subjects with AML or high-risk MDS. For all subjects, TP53wt status must be characterized by, at a minimum, no mutations noted in exons 5, 6, 7 and 8. Two treatment arms will enroll …

venetoclax
TP53
induction chemotherapy
cell transplantation
refractory acute myeloid leukemia (aml)
  • 67 views
  • 20 Oct, 2022
  • 7 locations