Fungal Infections Clinical Trials

A listing of Fungal Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 13 clinical trials
  • 12 Aug, 2021
  • 1 location
A Randomized Controlled Trial to Compare the Clinical Outcomes With Six Months of Therapy With Oral Itraconazole Versus Oral Voriconazole for Management of Treatment na ve Subjects With Chronic Pulmonary Aspergillosis

The current initial therapy for CPA is with six months of oral itraconazole. However, the response with six months of therapy has a response rate of 65-70% and has a relapse rate after stopping treatment of up to 50%. Voriconazole is a third-generation azole and a theoretical advantage of lower …

  • 08 Apr, 2021
  • 2 locations
Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization

This is a double-blind randomized placebo controlled trial that will investigate whether the use of three specific species of probiotics taken orally in pregnancy from 25 weeks gestation will reduce the incidence of Group B Streptococcus (GBS) colonization. Participants will take 2 capsules and 1 lozenge per day of either …

  • 23 Jan, 2021
  • 2 locations
Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis

This prospective, randomized, double-blind study will compare the effect of oral premedication of ibuprofen and methylprednisolone on the anesthetic efficacy of an Inferior Alveolar Nerve Block (IANB) in adult patients with symptomatic irreversible pulpitis.

  • 23 Jan, 2021
  • 1 location
Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation

The purpose of this pivotal study is to determine if intravenous Rezafungin is efficacious and safe in the prevention of invasive fungal diseases when compared to the standard antimicrobial

acute undifferentiated leukemia
refractory anemia with excess blasts
refractory cytopenia with multilineage dysplasia
  • 07 Sep, 2021
  • 23 locations
Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment

This is a multicenter, open label, non-comparator, single arm study to evaluate the efficacy and safety of ibrexafungerp (SCY-078) in patients 18 years of age with a documented fungal disease

  • 23 Jun, 2021
  • 42 locations
SVT-15652 Otic Solution for the Treatment of Otomycosis.

Multicenter, randomized, 2-arm parallel-group, double blind, placebo-controlled study in patients suffering from Otomycosis. This study will compare the efficacy and safety of SVT-15652 otic solution to that of Placebo, when administering one vial twice daily during 14 days.

  • 28 Mar, 2021
Efficacy Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis

Recruitment of at least 10 adult patients (men and women) among individuals affected and admitted to the hospitals identified for the clinical study. All patients shall be between 18 and 75 years of age, with confirmed diagnosis of cryptococcosis or aspergillosis . During therapy (14 days) and examination (28 days), …

  • 08 Nov, 2020
  • 1 location
Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

pruritus in patients with the mycosis fungoides (MF) or Szary syndrome (SS) Forms of Cutaneous T-cell Lymphoma (CTCL). This study will also determine if there is systemic absorption of the drug in a subset

sezary syndrome
cutaneous t-cell lymphoma
skin biopsy
  • 16 Aug, 2021
  • 32 locations
Antifungal Prophylaxis in Pediatric Acute Leukemia

Hypothesis:Oral Voriconazole will be as effective as intravenous Amphotericin B as antifungal prophylaxis in induction of acute leukemia (ALL, AML) in pediatric patients, with less toxicity and more convenience.

  • 07 Nov, 2020
  • 1 location