Pain; Bone Neoplasms; Neoplasm Metastasis Clinical Trials

A listing of Pain; Bone Neoplasms; Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment

18F-sodium fluoride (18F-NaF) was already investigated numerous times in the last 40 years as a PET alternative to standard 99m-technetium-derived bone scintigraphy. However, lack of universal tracer availability and higher costs contributed to the failure of 18F-NaF to systematically supplant bone scintigraphy as a standard of care. Recently, an isotope …

  • 0 views
  • 04 Oct, 2022
  • 2 locations
Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure

This is a randomized double-blind control trial evaluating the use Tranexamic acid (TXA) to decrease blood loss and transfusion requirements in pediatric and young adult cancer patients undergoing a limb salvage procedure that frequently requires perioperative or post-operative transfusions of blood products. Primary Objective To evaluate the difference in intra-or …

absolute neutrophil count
cancer
  • 0 views
  • 13 Jun, 2022
  • 1 location
Massive Implants the Next Generation (MING)

The study will review the use of massive segmental replacements in the femur, which have a porous collar with and without HA, and autologous stem cell augment. This is a randomised controlled trial.

cancer
revision procedure
bone cancer
  • 7 views
  • 19 Jun, 2022
  • 1 location
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases (FURTHER)

The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP. This multicenter, three-armed randomized controlled trial will be performed in six hospitals in four European countries, and will …

metastasis
bone metastases
focused ultrasound therapy
heat
hifu
  • 16 views
  • 01 Mar, 2022
  • 2 locations
9-ING-41 in Patients With Advanced Cancers

GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers.

kidney function tests
corticosteroids
carboplatin
liver metastasis
MRI
  • 795 views
  • 29 May, 2022
  • 10 locations
Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II

This study aims at evaluating the value of various artificial intelligence based techniques to improve the characterization and image post-processing for patients with musculoskeletal tumors.

imaging techniques
  • 0 views
  • 24 Jan, 2021
  • 1 location
An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry

Translational studies in cancer research can be impeded by the lack of high-quality clinical data that can be correlated with research questions. This is particularly true in the case of rare diseases, such as bone and soft tissue tumors. It is therefore the purpose of this study to create a …

cancer
  • 6 views
  • 04 Oct, 2022
  • 1 location
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to …

pheochromocytoma
paraganglioma
adrenal pheochromocytoma
genetic analysis
crest
  • 116 views
  • 07 Oct, 2022
  • 1 location
Multicentric Bone Tumor Imaging Report and Data System

In this study a previously described structured multimodality image report system for the characterization of focal bone lesions is evaluated in a larger patient population. The objective of this study is to evaluate the performance of this tool stratifying the malignancy risk of bone tumors.

  • 0 views
  • 27 Jun, 2021
  • 9 locations
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery. The study will look at the level of function for a period of …

sarcoma
osteocalcin
bone graft
n-telopeptide
  • 108 views
  • 13 Jul, 2022
  • 3 locations