Hereditary Angioedema Clinical Trials

A listing of Hereditary Angioedema medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 12 clinical trials
OASIS-HAE: A Study to Evaluate the Safety and Efficacy of Donidalorsen (ISIS 721744 or IONIS-PKK-LRx) in Participants With Hereditary Angioedema (HAE)

The purpose of this study is to evaluate the safety and efficacy of donidalorsen in participants with HAE and effect of donidalorsenon the quality and pattern of HAE attacks and their impact on quality of life (QoL).

angioedema
  • 1 views
  • 11 Jul, 2022
  • 16 locations
A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (KVD824-201)

A study to assess whether different doses of KVD824 are effective in preventing attacks of Hereditary Angiodedema Type I or Type II.

  • 0 views
  • 22 Jul, 2022
  • 32 locations
NTLA-2002 in Adults With Hereditary Angioedema (HAE) (NTLA-2002)

This study will be conducted to evaluate the safety, tolerability, activity, pharmacokinetics, and pharmacodynamics of NTLA-2002 in adults with Hereditary Angioedema (HAE).

angioedema
  • 0 views
  • 26 Jul, 2022
  • 3 locations
A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

This study is a randomized, double-blind, placebo-controlled, phase III, three-way crossover clinical trial evaluating the efficacy and safety of KVD900, in the treatment of hereditary

angioedema
c1 inhibitor (human)
  • 4 views
  • 13 Jul, 2022
  • 15 locations
A Study of Lanadelumab (SHP643) in Chinese Participants With Hereditary Angioedema (HAE)

The main aim of this study is to evaluate the safety of lanadelumab in Chinese participants with HAE. Participants will be treated with a subcutaneous injection of lanadelumab every two weeks for 26 weeks. During the study, each participant will make 16 visits to study clinics.

  • 0 views
  • 27 Jul, 2022
  • 4 locations
A Study to Assess the Long-Term Safety and Efficacy of Donidalorsen in the Prophylactic Treatment of Hereditary Angioedema (HAE)

The purpose of this study is to evaluate the long-term safety and efficacy of donidalorsen in people with HAE and the effects of donidalorsen on the number of HAE attacks and their impact on quality of life (QoL).

  • 0 views
  • 09 Aug, 2022
Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

This study evaluates the safety and efficacy of PHA-022121 administered orally for prophylaxis against angioedema attacks in patients with hereditary angioedema (HAE). The study will have 3

hereditary angioedema type i
angioedema
  • 0 views
  • 23 Jul, 2022
  • 20 locations
A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema (HAErmony-1)

This is a Phase 1/2, single-arm, open-label, dose-escalation and dose-expansion study of BMN 331 for the treatment of hereditary angioedema (HAE) due to C1 Esterase Inhibitor (C1-INH) protein

deficit
deficiency
angioedema
c1 inhibitor (human)
  • 0 views
  • 10 Jul, 2022
  • 4 locations
A Study of the Burden of Illness and Treatment Patterns in Teenagers and Adults With Hereditary Angioedema (BOISTERN)

This study is about teenagers and adults with hereditary angioedema (HAE) type I and type II. In this study, the burden of illness means the impact of HAE in terms of long-term health outcomes

angioedema
  • 0 views
  • 24 May, 2022
  • 4 locations
A Survey of Lanadelumab in Participants With Hereditary Angioedema

This study is a survey in Japan of Lanadelumab used to treat people with hereditary angioedema (HAE). The study sponsor will not be involved in how the participants are treated but will provide

  • 0 views
  • 14 Jul, 2022
  • 1 location