Cushing's Disease Clinical Trials

A listing of Cushing's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 13 clinical trials
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with Cushing's disease.

lci699
ACTH
cushing's syndrome
osilodrostat
dexamethasone suppression test
  • 6 views
  • 10 May, 2022
  • 6 locations
An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women

bone quality as well as mood and quality of life in a female patient with mild hypercortisolism from adrenal overproduction of cortisol. Many people with adrenal nodules, or non-cancerous growths in

  • 4 views
  • 16 Sep, 2021
  • 1 location
Postoperative Thrombosis Prevention in Patients With CD

Patients with Cushing disease was randomized to 2 groups. After surgery, the patients were managed with mechanical prevention or mechanical prevention plus anticoagulant drugs(LMWH followed by

thrombosis
clot
lmwh
rivaroxaban
postoperative thrombosis
  • 0 views
  • 27 Jul, 2022
  • 4 locations
SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome (RESCUE)

This is a randomized, placebo-controlled, crossover study of SPI-62 in subjects with ACTH-dependent Cushing's syndrome. Subjects will receive each of the following 2 treatments for 12 weeks: SPI-62 and matching placebo

  • 0 views
  • 11 Jul, 2022
  • 3 locations
Exploring the Effects of Corticosteroids on the Human Hippocampus

atrophy are reported in patients with excessive CS release due to Cushing's disease, and, by our group, in patients receiving prescription CS therapy. These findings have important implications for

major depressive disorder
depressive symptoms
depressed mood
Accepts healthy volunteers
depressive disorder
  • 103 views
  • 21 Mar, 2022
  • 1 location
Nasal Packing Following Endoscopic Endonasal Pituitary Resection

There is considerable controversy about the use of nasal packing following endoscopic endonasal resection of pituitary tumors as a necessary treatment amongst Rhinology-Skull Base Surgeons. The justification for the routine use of nasal packing following pituitary surgery is not clear as this practice is not used for equally extensive sinus …

nasal packing
surgery for pituitary tumors
pituitary disorders
  • 15 views
  • 06 May, 2022
  • 1 location
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

causes Cushing disease. This disease causes many problems. Some of these problems might persist after the disease is cured. Objective To find out the long-term

linkage analysis
cushing's syndrome
stimulation test
Accepts healthy volunteers
dxa scan
  • 104 views
  • 27 Jul, 2022
  • 1 location
Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease

patients with Cushing's disease. Patients with Cushing's disease and treated with pasireotide s.c. alone and in combination with other therapies will be monitored. For this study, each enrolled patient

cushing's syndrome
som230
pasireotide
  • 70 views
  • 02 Jun, 2022
  • 5 locations
Seoul National University Pituitary Disease Cohort Study (SNU-PIT)

The purpose of this study is to investigate the treatment and natural history of pituitary disease. We have a longstanding interest in pituitary disease including acromegaly, central diabetes insipidus, and nonfunctioning pituitary adenoma. We will continue to follow patients and recruit new patients for treatment and follow-up. Blood and pituitary …

pituitary disorders
acromegaly
pituitary adenoma
craniopharyngioma
adenoma
  • 107 views
  • 01 Mar, 2022
  • 1 location
An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

of cortisol secretion in pediatric patients with Cushing disease. Continuation of this protocol will eventually lead to new, separate protocols that will address all aspects of diagnosis of

cushing's syndrome
central nervous system tumors
linkage analysis
craniopharyngioma
Accepts healthy volunteers
  • 181 views
  • 08 Aug, 2022
  • 1 location