Low Testosterone Clinical Trials

A listing of Low Testosterone medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 115 clinical trials
ABI-009 an mTOR Inhibitor for Patients With Severe Pulmonary Arterial Hypertension

mTOR activation has been shown to be relevant in the development and progression of pulmonary hypertension. Inhibition of mTOR has been shown to reverse or regress pulmonary hypertension in animal models. ABI-009 is an albumin-bound mTOR inhibitor with improved penetration in lung tissue.

left ventricular end-diastolic pressure
pulmonary arterial hypertension
primary pulmonary hypertension
congenital heart defects
pulmonary function test
  • 1 views
  • 27 Feb, 2021
  • 6 locations
Effect of Exercise Training in Patients With Pulmonary Hypertension

Pulmonary Hypertension (PH) is a serious disease with a dismal prognosis when left untreated. Advances in medical therapy have improved survival according to recent registries and systematic reviews, but are associated with high healthcare costs. Earlier studies in Heidelberg, Germany showed good evidence for the effect of exercise training on …

pulmonary arterial pressure
diuretics
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis

A phase 2b, open label study to assess the safety and efficacy of increasing doses of pulsed, inhaled nitric oxide (iNO) in subjects with pulmonary fibrosis and sarcoidosis on long term oxygen therapy followed by a long term extension study

left ventricular end-diastolic pressure
right heart catheterization
rheumatism
sarcoidosis
pulmonary fibrosis
  • 171 views
  • 13 May, 2021
  • 6 locations
Impedancemetry in Patients Monitored for Pulmonary Hypertension

Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension

  • 1 views
  • 26 Jan, 2021
  • 1 location
Effects of Inspiratory Muscle Training in Patients With Pulmonary Hypertension

This study aims to determine the possible effects of inspiratory muscle training on cardiovascular, respiratory, physical and psychosocial functions in patients with PH.

  • 0 views
  • 25 Jan, 2021
  • 1 location
MK-5475 in Participants With Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease (PH-COPD) (MK-5475-006)

The main purpose of this study is to assess MK-5475 in the PH-COPD population by evaluating the safety, pharmacokinetics (PK), changes in pulmonary vascular resistance (PVR), and changes in pulmonary blood volume (PBV) after administration. The primary study hypothesis is that the MK-5475 results in superior reduction of the mean …

right heart catheterization
pulmonary disease
dyspnea
  • 19 views
  • 24 Sep, 2021
  • 6 locations
Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a severe, progressive and potentially fatal disease that impairs the pulmonary circulation and leads to right ventricular failure. One of the world most prevalent etiologies of PAH is schistosomiasis-associated pulmonary arterial hypertension (Sch-PAH). New drugs have emerged to treat other forms of PAH, but their …

endothelin receptor antagonist
phosphodiesterase-5 (pde-5) inhibitor
pulmonary arterial hypertension
endothelin
right ventricular failure
  • 0 views
  • 26 Jan, 2021
  • 1 location
THERAPY-HYBRID-BPA Trial

Riociguat could improve the exercise capacity and residual symptoms in patients with chronic thromboembolic pulmonary hypertension (CTEPH) even after normalization of pulmonary arterial pressure by balloon pulmonary angioplasty (BPA). This randomized controlled trial study aimed to clarify whether the improvement of peak cardiac index (CI) during exercise maintains or not …

right heart catheterization
riociguat
  • 2 views
  • 26 Jan, 2021
  • 1 location
Levosimendan Administration in Pulmonary Hypertension

The aim of the study is to examine the pharmacokinetics and pharmacodynamic properties of Levosimendan in cardiac surgery patients with pulmonary hypertension and impaired right ventricular function.

left ventricular dysfunction
anesthesia
hypertension
levosimendan
  • 0 views
  • 30 Jan, 2021
  • 1 location
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

left ventricular end-diastolic pressure
right heart catheterization
pulmonary arterial hypertension
oxygen saturation
prostaglandin
  • 10 views
  • 20 Jul, 2021
  • 9 locations