Heart Defect Clinical Trials

A listing of Heart Defect medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 231 clinical trials
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Seeking Oklahomans with Congestive Heart Failure who are unable to walk across a room without experiencing shortness of breath and fatigue.

Seeking Oklahomans with Congestive Heart Failure who are unable to walk across a room without experiencing shortness of breath and fatigue.

  • 326 views
  • 08 Nov, 2020
  • 1 location
None
Study of Sotatercept in Newly Diagnosed Intermediate- and High-risk PAH Patients

The objective of this study is to evaluate the effects of sotatercept treatment (plus background PAH therapy) versus placebo (plus background PAH therapy) on time to clinical worsening (TTCW) in participants who are newly diagnosed with PAH and are at intermediate or high risk of disease progression.

  • 0 views
  • 24 Oct, 2021
  • 2 locations
None
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (STELLAR)

The objectives of this study are to evaluate the efficacy and safety of sotatercept treatment (plus background PAH therapy) versus placebo (plus background PAH therapy) at 24 weeks in adults with PAH.

  • 0 views
  • 24 Sep, 2021
  • 69 locations
None
Pediatric Exercise With Congenital Heart Defects (Kinderturnen Mit Angeborenem Herzfehler)

Children with congenital heart defects have shown to develop motor coordinative deficiencies. In this study we want to show that a motor pedagogic physical training can improve the

congenital heart defects
  • 17 views
  • 07 Nov, 2020
  • 2 locations
None
Effect of Feeding With Nutrient Dense Formula in Malnourished Infants and Children With Congenital Heart Defects

Infants with congenital heart disease (CHD) are usually born with a normal weight but develop malnutrition over time, and about 20-50% of these children are usually malnourished. Malnutrition in these patients is multifactorial. To compensate for the increased need for infants and children with CHD, an increase in their caloric …

  • 0 views
  • 10 Oct, 2021
  • 1 location
None
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery

Cardiopulmonary bypass and arrest of the heart during cardiac surgery are necessary to allow the surgeon to perform heart operations. However, these processes can cause injury to the heart which may worsen post-operative outcomes. In fact, the effects of these injuries may continue after surgery, and lead to a long-term …

  • 0 views
  • 20 Aug, 2021
  • 1 location
None
  • 0 views
  • 25 Mar, 2021
  • 1 location
None
Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass

Newborn babies and children with congenital heart defects who need heart surgery need to be placed on the heart-lung machine for heart surgery. In order to use the heart-lung machine, the

cardiopulmonary bypass
heart surgery
congenital heart defects
  • 0 views
  • 03 Feb, 2021
None
Randomized Evaluation of Octreotide Versus Compazine for Emergency Department Treatment of Migraine Headache

octreotide use. Electrocardiogram analyses showed no newly occurring or worsening of known cardiac abnormalities 2 and 24 h after injection with octreotide. 5 Levy et. al also compared octreotide

dihydroergotamine
metoclopramide
sumatriptan
acute treatment
vomiting
  • 286 views
  • 07 Nov, 2020
  • 1 location
None
Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes

Beyond EV-B, there are clinical observations to implicate other viruses in birth defects, including CHD. Since the Rubella epidemic of 1960s', however, viruses have received little attention and certainly no comprehensive study, especially using next generation sequencing (NGS), has been undertaken in this context. The current pandemic as well as …

fever
diabetes
influenza
  • 0 views
  • 23 Aug, 2021
  • 2 locations