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Appendicitis Clinical Trials

A listing of Appendicitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (36) clinical trials

Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis

The study will include patients aged 16 and over, with a first admission with right iliac fossa pain and a raised white cell count or C-reactive protein. Patients will be randomised electronically in a 1:1 ratio either to undergo emergency appendectomy or to receive intravenous antibiotics as an inpatient, until ...


Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

Background Acute appendicitis is the commonest surgical emergency in children. The lifetime risk of developing appendicitis is 7-8%, with a peak incidence in the teenage years.The associated financial burden of treating appendicitis is very large. For over 100 years, surgical removal of the appendix has been deemed necessary to effectively ...

Phase N/A

A clinical trial sponsored by Mauro Podda for a research study for the treatment of Acute Appendicitis, Appendicitis Recurrent, Appendectomy, Antibiotic Therapy

On September the 15th, 2015, Italian surgeons, radiologists and pathologists with a special interest and expertise in the diagnosis and management of Acute Appendicitis (AA), met up under the auspices of the Italian Society of Hospital Surgeons (ACOI) in Oristano (Italy) to constitute the ACTUAA collaborative working group. The main ...

Phase N/A

Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies

Aim The aim of the study is to investigate which infectious diseases might mimic the symptoms of acute appendicitis to a degree that cause a diagnostic laparoscopy or laparoscopic appendectomy. Primary outcome A comparison of the incidence of Yersinia spp. (enterocolitica and/or pseudotuberculosis) infection diagnosed by PCR on rectal swabs ...

Phase N/A

Finding Evidence to Treat Or Reassure in Appendicitis (FETOR)

Acute appendicitis is the most common surgical emergency in childhood. Despite access to current diagnostic modalities, diagnosis may be challenging since the child may have difficulty in articulating symptoms. Additionally there is a high frequency of atypical presentation and rapid progression. Delayed diagnosis in children is reported as being up ...

Phase N/A

Multi-institutional Trial of Non-operative Management of Appendicitis

Several randomized controlled trials comparing appendectomy to antibiotics alone in adults with acute appendicitis have been reported from non-U.S. countries. These studies reveal that non-operative management of appendicitis is a safe treatment for appendicitis and is associated with a significantly lower risk of complications than appendectomy. We have recently completed ...

Phase N/A

Point of Care Ultrasound for Evaluation of Suspected Appendicitis in the Emergency Department

BACKGROUND Increasing concerns have been raised over the past several years regarding the degree of radiation exposure in patients being evaluated for abdominal complaints. A deepening body of literature supports the use of ultrasound for the evaluation of appendicitis. In particular, ultrasound is being promoted as first line testing in ...

Phase N/A

Evaluation of Local Anesthetic at Incision Site

This is a prospective randomized-controlled pilot study of 100 pediatric subjects, recruited through Phoenix Children's Hospital and Pediatric Surgeons of Phoenix, who will undergo a laparoscopic appendectomy (LA) for acute non-perforated appendicitis. The reviewer and subject will be blind to the treatment to help prevent bias. The subjects will be ...

Phase N/A

Point of Care 3D Ultrasound for Pediatric Appendicitis: a Pilot Study

Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound for pediatric appendicitis. The study will use a newly developed acquisition method and post-processing technique to create three dimensional image models of the abdomen. Study activities and population ...

Phase N/A

A Retrospective Study of the Feasibility of Ambulatory Appendicectomy for Acute Appendicitis (Based on Data From the PMSI French National Hospital Information System) in the Adults Hospitalized Between December 2013 and December 2014

Acute appendicitis is a frequent surgical emergency, with an estimated incidence of about 80,000 cases a year (in France). It mainly affects young adults but is associated with a low complication rate and a short stay in hospital. Ambulatory treatment is an innovative type of care in which the patient ...

Phase N/A