Vaginal Atrophy Clinical Trials

A listing of Vaginal Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 261 clinical trials
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

Background Changes in how a person s body burns energy or calories can affect their weight over time. The lowest level of energy the body needs to function is called basal metabolic rate. In the cold, we burn extra energy, even before we start to shiver. This is called non-shivering …

Accepts healthy volunteers
blood test
  • 321 views
  • 21 Sep, 2022
  • 1 location
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers (ECOG)

Acoustic overexposure can induced temporary or hearing loss. Usually hearing loss is associated with cochlear cell damages. Recently, a new pathological entity was described and called "hidden hearing loss". In animal model, the histopathology revealed a selective reduction in the number of auditory fibers, resulting in a decrease in the …

Accepts healthy volunteers
  • 8 views
  • 20 Feb, 2022
  • 1 location
Evaluating the Clinical Value of Traditional Chinese Medicine in the Adjuvant Therapy of Triple-negative Breast Cancer

This is a prospective, single site, randomized, double-blind Phase III clinical trial to evaluate the clinical value of Traditional Chinese Medicine in the adjuvant therapy of triple-negative breast cancer patients.

EGFR
metastasis
progesterone
epidermal growth factor receptor
triple-negative breast cancer
  • 10 views
  • 24 Jan, 2021
  • 1 location
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

Glucose starvation and metformin have synergistic antitumor effects that are mediated through the concomitant inhibition of glycolysis and mitochondrial oxidative phosphorylation. The BREAKFAST trial will evaluate the antitumor activity of combining cyclic fasting-mimicking diet (FMD), which reproduces the in vitro effects of glucose starvation, plus/minus metformin with standard preperative anthracycline-taxane …

gilbert's syndrome
anthracyclines
cyclophosphamide
progesterone
mammogram
  • 34 views
  • 25 Jan, 2021
  • 1 location
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy

This study will evaluate the efficacy and safety of antharcycline-based adjuvant chemotherapy compared with observation in triple negative breast cancer (TNBC) patients with residual invasive disease after platinum and taxanes based neoadjuvant chemotherapy.

breast surgery
taxane
epirubicin
erbb2
cyclophosphamide
  • 35 views
  • 25 Jan, 2021
  • 1 location
Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

This is single arm study of a window of opportunity in which participants with previously untreated triple negative breast cancers (TNBC) who are candidates for potentially curative surgery will receive lenvatinib 12 mg BID for 7 and pembrolizumab 200 mg IV on day 1 prior to surgery

gilbert's syndrome
EGFR
metastasis
progesterone
tumor cells
  • 0 views
  • 08 Jul, 2022
  • 1 location
Neoadjuvant Treatment of Early Triple-negative Breast Cancer With Chidamide and Chemotherapy

Objective to evaluate the efficacy and safety of neoadjuvant therapy with Chidamide combined with chemotherapy for stage II - III triple-negative breast cancerand to compare the efficacy and safety of chemotherapy with Chidamide and chemotherapy alone in the neoadjuvant treatment of stage II - III triple-negative breast cancer

docetaxel
erbb2
epirubicin
HER2
  • 0 views
  • 27 Jan, 2021
  • 1 location
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

The purpose of this research is to measure the extent of lung inflammation between different groups of participants using a radioactive tracer called [18F]NOS. A radioactive tracer is a type of imaging drug that is labeled with a radioactive tag and injected into the body.

Accepts healthy volunteers
  • 183 views
  • 28 Jul, 2022
  • 1 location
A Study of the Efficacy and Safety of Camrelizumab Plus Radiotherapy for Patients With Early Triple-Negative Breast

This is a open-labeled, single-arm, Investigator-initiated clinical trial of camrelizumab (an anti-PD-1 antibody) in combination with radiotherapy in patients with early triple-negative breast cancer. We will enroll 60 subjects. This study aims to evaluate the efficacy and safety of camrelizumab combined with radiotherapy in the treatment of early TNBC

mastectomy
erbb2
serum total bilirubin
metastasis
mammogram
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Prospective Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After NAC in TNBC

Positive circulating tumor DNA(ctDNA) status is associated with worse prognosis in breast cancer, especially triple-negative breast cancer(TNBC). Our trial aims to improve the outcome of TNBC patients by using ctDNA to identify patients with high relapse risk. ctDNA positive patients will be randomized to receive boost therapy or standard therapy …

erbb2
metastasis
immunohistochemistry
mammogram
capecitabine
  • 0 views
  • 18 Mar, 2021
  • 1 location