Vaginal Atrophy Clinical Trials

A listing of Vaginal Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 354 clinical trials
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Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis

The primary objective is to determine whether Leukotriene A4 hydrolase (LTA4H) genotype, defined at randomisation, determines dexamethasone's clinical effectiveness when added to the first 6-8 weeks of anti-tuberculosis treatment of TBM. The investigators will conduct a LTA4H genotype stratified, parallel group, randomised, double blind, placebo-controlled multi-centre Phase III non-inferiority trial …

isoniazid
tb chemotherapy
tuberculosis treatment
corticosteroids
rifampin
  • 53 views
  • 21 Oct, 2021
  • 3 locations
None
NordicTrip a Translational Study of Preoperative Chemotherapy in TNBC

Primary aim: Pathological complete response rate after preoperative chemotherapy is the primary end-point of the study, which will be evaluated by comparing the effects of neoadjuvant administration of a carboplatin-based treatment and treatment adding capecitabine on Pathological Complete Response (pCR).

HER2
epirubicin
epidermal growth factor
immunohistochemistry
cyclophosphamide
  • 5 views
  • 26 Jan, 2021
  • 35 locations
None
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

This is a phase I/Ib, open label study. The escalation portion will characterize the safety and tolerability of DKY709 and DKY709 in combination with PDR001 in subjects with NSCLC or melanoma who have received prior anti-PD-1/PD-L1 therapy, or subjects with NPC. After the determination of the MTD/RD for a particular …

cancer
measurable disease
solid tumour
core needle biopsy
programmed cell death 1 ligand 1
  • 113 views
  • 28 Nov, 2021
  • 9 locations
None
Prospective Biobanking Study in Ovarian Breast and Head and Neck Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself Its Microenvironment and Immune Response (SCANDARE)

SCANDARE is a prospective biobanking study on tumor (+/- nodes), plasma and blood samples at different time points in ovarian, triple negative breast and head and neck cancer patients. This study will allowed to identify new molecular and/or immunological biomarkers associated with clinical and biological features of the tumors. All …

cancer
triple-negative breast cancer
breast cancer
cancer chemotherapy
ovarian cancer
  • 3 views
  • 28 Jan, 2021
  • 2 locations
None
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

atherosclerosis
hyperlipidemia
MRI
angiography
heart disease
  • 105 views
  • 04 Sep, 2021
  • 1 location
None
A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors

This study will evaluate the safety, tolerability, and preliminary antitumor activity of CAN04 both as a monotherapy and in combination with standard of care treatment in subjects with solid cancer tumors. Following completion of the first part, the dose escalation cohorts, and determination of maximum tolerated dose or recommended phase …

lung cancer
measurable disease
cancer chemotherapy
gemcitabine
chemotherapy regimen
  • 244 views
  • 20 Aug, 2021
  • 37 locations
None
A Study to Determine the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of ABBV-927 With ABBV-368 Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and a dose-expansion phase. The dose-expansion phase can begin once the recommended phase 2 dose/maximum …

solid tumour
epidermal growth factor
cancer treatment
systemic therapy
paclitaxel
  • 52 views
  • 01 Aug, 2021
  • 38 locations
None
GEN1029 (HexaBody -DR5/DR5) Safety Trial in Patients With Malignant Solid Tumors

The purpose of the trial is to evaluate the safety of GEN1029 (HexaBody-DR5/DR5) in a mixed population of patients with specified solid tumors

measurable disease
solid tumour
kidney function test
renal function test
renal function
  • 214 views
  • 24 Jul, 2021
  • 6 locations
None
First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

The purpose of this study is to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Antitumor Activity of AZD8701 Alone and in Combination with Durvalumab (MEDI4736) in Adult Subjects with Select Advanced Solid Tumors

lung cancer
medi4736
solid tumour
small lung
durvalumab
  • 52 views
  • 31 Oct, 2021
  • 12 locations
None
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies

This clinical trial is evaluating a drug called BT8009 alone and in combination with nivolumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The main goals of this study are to: Find the recommended dose of BT8009 …

lung cancer
carcinoma
mammogram
brain metastases
cancer of the ovary
  • 99 views
  • 11 Nov, 2021
  • 16 locations