Vaginal Atrophy Clinical Trials

A listing of Vaginal Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 353 clinical trials
None
A Phase 3 Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib Carelizumab Plus Nab-paclitaxel and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.

This randomized, open-label phase 3 study will evaluate the safety and efficacy of Carelizumab (an engineered anti-programmed death-ligand 1 [PD-1] antibody) in combination with Nab-paclitaxel and Apatinib, carelizumab plus nab-paclitaxel, and Nab-paclitaxel in Patients with Unresectable Locally Advanced or Metastatic Triple Negative Breast Cancer. Participants will be randomized in a …

HER2
paclitaxel
triple negative breast cancer
stage iv breast cancer
triple-negative breast cancer
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC. During the dose-escalation part of each treatment arm, patients will be treated with fixed doses …

progesterone receptor
estrogen
triple negative breast cancer
estrogen receptor
adjuvant chemotherapy
  • 44 views
  • 05 Aug, 2021
  • 13 locations
None
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer

This study is designed to determine the efficacy and safety of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple negative breast cancer

trastuzumab
HER2
paclitaxel
triple negative breast cancer
cancer
  • 400 views
  • 03 Nov, 2021
  • 65 locations
None
Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC

The GLORIA study is a Phase III, randomized, open-label study to prospectively evaluate the efficacy and safety of adagloxad simolenin (OBI 822)/OBI-821 in the adjuvant treatment of patients with high risk, early stage Globo-H Positive TNBC.

progesterone receptor
invasive breast cancer
renal function test
estrogen
metastasis
  • 323 views
  • 22 Nov, 2021
  • 146 locations
None
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC)

measurable disease
breast cancer
formalin-fixed paraffin-embedded
cancer
paclitaxel
  • 1388 views
  • 24 Nov, 2021
  • 335 locations
None
Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico

Primary Objective: To describe the antibody titers to the antigens (meningococcal serogroups A, C, Y, and present in MenACYW conjugate vaccine or Menveo measured by serum bactericidal assay using human complement (hSBA), for Groups 1 and 2 when administered concomitantly with routine pediatric vaccines in healthy infants and toddlers in …

Accepts healthy volunteers
  • 7 views
  • 09 Nov, 2021
  • 22 locations
None
S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it …

trastuzumab
hypertension
metastasis
human epidermal growth factor
ace inhibitor
  • 200 views
  • 18 Nov, 2021
  • 129 locations
None
Effects of Arousal and Stress in Anxiety

This study has several parts. One part will examine the influence of factors such as personality and past experience on reactions to unpleasant stimuli. Others will examine the effect of personality and emotional and attentional states on learning and memory. When confronted with fearful or unpleasant events, people can develop …

Accepts healthy volunteers
  • 563 views
  • 01 Dec, 2021
  • 1 location
None
Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis

The primary objective is to determine whether Leukotriene A4 hydrolase (LTA4H) genotype, defined at randomisation, determines dexamethasone's clinical effectiveness when added to the first 6-8 weeks of anti-tuberculosis treatment of TBM. The investigators will conduct a LTA4H genotype stratified, parallel group, randomised, double blind, placebo-controlled multi-centre Phase III non-inferiority trial …

tb chemotherapy
tuberculosis treatment
meningitis
corticosteroids
rifampin
  • 53 views
  • 21 Oct, 2021
  • 3 locations
None
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

This is a phase I/Ib, open label study. The escalation portion will characterize the safety and tolerability of DKY709 and DKY709 in combination with PDR001 in subjects with NSCLC or melanoma who have received prior anti-PD-1/PD-L1 therapy, or subjects with NPC. After the determination of the MTD/RD for a particular …

measurable disease
metastasis
solid tumour
programmed cell death 1 ligand 1
cancer
  • 113 views
  • 29 Nov, 2021
  • 9 locations