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Carotid Artery Disease Clinical Trials

A listing of Carotid Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (60) clinical trials

CREST-2 is two parallel multi-center randomized, observer-blinded endpoint clinical trials. One trial will assess treatment differences between intensive medical management alone compared to CEA plus intensive medical management. The parallel trial will assess treatment differences between intensive medical management alone compared to CAS plus intensive medical management. Intensive medical management ...

Phase N/A

CREST-2 is two parallel multi-center randomized, observer-blinded endpoint clinical trials. One trial will assess treatment differences between intensive medical management alone compared to CEA plus intensive medical management. The parallel trial will assess treatment differences between intensive medical management alone compared to CAS plus intensive medical management. Intensive medical management ...

Phase N/A

The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death in patients with coronary or peripheral artery disease.

Phase N/A

Research study to compare surgery, either a stent, or endarterectomy, and/or intensive medical management. Carotid arteries are the main arteries feeding your brain. The narrowing increases your risk of having a stroke. The narrowing is caused by a thickened area called a plaque.  

Phase N/A

The objective of this study is to evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.  The stent is a self-expanding implant with a ...

Phase N/A

Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control

Cerebrovascular accident (CVA) constitutes a major health public problem. This represents the second cardiovascular death cause. CVA is ischemic in 80% of cases. Atheroma of large arteries, mainly carotid, is involved in about 20% of cases. After several high grade studies (NASCET, ECST, ACAS, ACST), carotid surgery is based on ...

Phase N/A

Hemodynamics and Autonomic and Cognitive Performance After Carotid Revascularization Procedures

Hypothesis and Significance: Late clinical outcome and prognosis after CAS may be inferior to that after CEA in terms of autonomic modulation, hemodynamic remodeling, and cognitive function. Specific Aim: 1) To compare the impact of CEA and CAS on long-term post-operative baroreceptor function and on cognitive brain function, and analyze ...

Phase N/A

3D Multi-Contrast Atherosclerosis Characterization of the Carotid Artery

All participants will undergo the conventional MRI protocol and the new imaging protocol using our developed techniques. They may have either non-contrast scans or contrast-enhanced scans or both depending on the stage of development. The comparison results between the two protocols will be used to evaluate the performance of the ...

Phase N/A

Atherosclerotic Plaque Characteristics Associated With a Progression Rate of the Plaque in Carotids and a Risk of Stroke

Objectives and aims The objective of the project is to identify measurable features of atherosclerotic plaque in carotids associated with plaque progression and increased stroke/TIA risk using duplex sonography and digital B-mode image analysis. The project aims to identify characteristics of carotic atherosclerotic plaque in ultrasound B-mode associated with a ...

Phase N/A

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

CREST-H sites will be drawn from actively-enrolling CREST-2 centers. The additional information obtained in CREST-H in this protocol will be the MR imaging, which will be done at baseline for all patients enrolled in CREST-H, and at 1 year for those with hemodynamic impairment at baseline. The protocol will require ...

Phase N/A