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Carotid Artery Disease Clinical Trials

A listing of Carotid Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (84) clinical trials

Predictive Value of Neovascularization Within Asymptomatic Carotis Stenosis on CEUS

Background: Injection of ultrasound contrast agents, in conjunction with contrast specific imaging techniques, is increasingly accepted in clinical use for diagnostic ultrasound imaging. As microbubbles contrast agents appear to be ideal pure intravascular tracers to enhance the vascular lumen and more important to assess the dynamic spatial and temporal heterogeneity ...

Phase N/A

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Prevention of stroke involves managing and treating risk factors. Most strokes are caused when blood flow to a portion of the brain is blocked. One place this often happens is in the carotid artery. This blockage is called atherosclerosis or hardening of the arteries. The purpose of this trial is ...

Phase N/A

Structural Stability of Carotid Plaque and Symptomatology

This study examines the relationship between the structural stability of carotid atherosclerotic plaque forming at the bifurcation of the common internal/external carotids and the ability of such lesions to cause disease. The theory behind this work is the hypothesis that carotid atherosclerotic stroke presents not only as a classical episodic ...

Phase N/A

The CREST-2 Registry

Objectives Promote the rapid initiation and completion of enrollment in CREST-2 CAS will be performed by experienced operators Clinical outcomes will be closely monitored Prevent inappropriate use of CAS outside of the registry Registry Data Collection: The registry will leverage the existing data-collection infrastructure of the Society for Vascular Surgery's ...

Phase N/A

Essential Hypotension and Allostasis Registry

DEFINITIONS ARTERIAL BLOOD PRESSURE CLASSIFICATION Arterial Blood Pressure (ABP) is a complex physiological variable in regard to its measure, behavior between BP taken in the same visit at the office and between these and ABPM, chronobiology (different day time BP levels), evolution in time, meaning and classification. Not appropriate approach ...

Phase N/A

SONOlysis in Prevention of Brain InfaRctions During Internal Carotid Endarterectomy

Results of the NASCET, ECST and ACAS studies showed that carotid endarterectomy (CEA) was a beneficial therapy for patients with a symptomatic internal carotid artery (ICA) stenosis >50% and asymptomatic ICA stenosis >60%, resp. Surgical risk of CEA varied between 2 and 15 % and even clinically silent microembolism can ...

Phase N/A

Arachidonic Acid Metabolism in Carotid Stenosis Plaque in Diabetic Patients

Diabetes is associated with an increased risk of cardiovascular complications, as a reflection of the chronic inflammatory status. Monocytes-macrophages in diabetic subjects present impaired arachidonic acid metabolism. Moreover, atheromatous plaques in diabetic subjects seem to be significantly enriched in 2-AA-LPC (2-arachidonoyl-lysophosphatidylcholine) and are more inflammatory and more likely to rupture ...

Phase N/A

SVS VQI TransCarotid Revascularization Surveillance Project

Background Contemporary randomized trials of transfemoral carotid artery stenting (TF CAS) and carotid endarterectomy (CEA) have shown comparable long-term ipsilateral stroke prevention (>30 days) but have consistently demonstrated higher periprocedural (< 30 day) stroke rates, including contralateral stroke, compared with CEA, with the highest risk centered around "day zero". Potential ...

Phase N/A

Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Patients

The trial randomise patients with asymptomatic carotid artery narrowing in whom prompt physical intervention is thought to be needed, but there there is still substantial uncertainty shared by patient and doctor about whether surgery or stenting is the more appropriate choice. The study is looking at immediate risks (within one ...

Phase N/A

Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis

Currently, carotid duplex ultrasound is used for screening for ICA stenosis and must be performed by a trained and certified vascular technologist using advanced duplex imaging equipment and with subsequent interpretation by a trained physician. It would be of value to develop an accurate, reliable, low-cost, and easily accessible tool ...

Phase N/A