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Carotid Artery Disease Clinical Trials

A listing of Carotid Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (95) clinical trials

CREST-2 is two parallel multi-center randomized, observer-blinded endpoint clinical trials. One trial will assess treatment differences between intensive medical management alone compared to CEA plus intensive medical management. The parallel trial will assess treatment differences between intensive medical management alone compared to CAS plus intensive medical management. Intensive medical management ...

Phase N/A

CREST-2 is two parallel multi-center randomized, observer-blinded endpoint clinical trials. One trial will assess treatment differences between intensive medical management alone compared to CEA plus intensive medical management. The parallel trial will assess treatment differences between intensive medical management alone compared to CAS plus intensive medical management. Intensive medical management ...

Phase N/A

The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death in patients with coronary or peripheral artery disease.

Phase N/A

The objective of this study is to evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.  •  The stent is a self-expanding implant with a ...

Phase N/A

To evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.   •  The stent is a self-expanding implant with a rapid exchange delivery catheter.•  The Nanoparasol ...

Phase

Research study to compare surgery, either a stent, or endarterectomy, and/or intensive medical management. Carotid arteries are the main arteries feeding your brain. The narrowing increases your risk of having a stroke. The narrowing is caused by a thickened area called a plaque.  

Phase N/A

PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis

This study is a single center, open-label baseline controlled imaging study designed to demonstrate feasibility of PET imaging of radiopharmaceutical nanoparticle Cu[64]-25%CANF-Comb uptake by PET-MR. Patients will undergo Cu[64]-25%CANF-Comb PET-MR imaging of both carotid arteries. Both carotid arteries will be imaged at the same time. We hope to demonstrate differences ...

Phase

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives

ESH-CHL-SHOT will randomize about 7500 participants aged > or = 65 years with SBP > or = 140 mmHg or antihypertensive therapy, who have presented a stroke or TIA, within 1 to 6 months before randomization. The trial will investigate the effects of randomization to antihypertensive treatment of different intensities, ...

Phase

18F-choline and 18F-FDG PET-MR of Symptomatic Carotid Plaques

Accumulation and subsequent activation of inflammatory cells in the atherosclerotic plaques play an essential role in transforming a stable plaque into a vulnerable plaque at risk to rupture. On this basis, the study aims to evaluate the diagnostic performance of 18F-choline PET in identifying ongoing inflammation within atherosclerotic plaques. The ...

Phase

Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control

Cerebrovascular accident (CVA) constitutes a major health public problem. This represents the second cardiovascular death cause. CVA is ischemic in 80% of cases. Atheroma of large arteries, mainly carotid, is involved in about 20% of cases. After several high grade studies (NASCET, ECST, ACAS, ACST), carotid surgery is based on ...

Phase N/A