Pain (Pediatric) Clinical Trials

A listing of Pain (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 9 clinical trials
Oral NSAI Versus Paracetamol or Placebo as a Second Line Treatment for Renal Colics

Outpatients treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this matter. The aim of this study is to determine if an oral NSAI treatment is beneficial in patients discharged for the emergency departement after the first line treatment of a …

  • 18 views
  • 24 Jan, 2021
  • 1 location
Tramadol Hydrochnoride as Adjuvant to Local Anesthetic in Ultrasound Guided Erector Spinea Plane Block in Management of Chronic Chest Wall Cancer Pain

Chest wall pain is a severe and distressing symptom. The erector spinae plane block (ESPB) is an interfascial plane block where local anesthetic is injected between the erector spine muscle and the transverse process. It is a simple procedure, with easy sonographic landmarks, for postoperative analgesia in patients undergoing thoracic, …

  • 0 views
  • 26 Jan, 2021
  • 1 location
Tariquidar-ondansetron Combination in Neuropathic Pain

Prospective, randomized, double-blind, placebo controlled, cross-over proof of concept study. To determine the pharmacokinetics and tolerability of co-administration of 5-HT3R antagonist ondansetron with a P-glycoprotein inhibitor tariquidar, in patients with neuropathic pain.

  • 0 views
  • 18 Feb, 2021
  • 1 location
The Phosphodiesterase 3 Inhibitor Cilostazol as an Adjunct to Conventional Therapy in Patients With Osteoarthritis

Cilostazol is able to suppress the degradation of type II collagen in human chondrocytes induced by IL-1b. Cilostazol add-on for celecoxib therapy has synergistic anti-arthritic potential by inhibiting proinflammatory cytokine production in synovial fibroblasts through the IL-10/SOCS3 pathways, consequently leading to the inhibition of synovial cell proliferation and overcoming the …

  • 0 views
  • 27 Mar, 2021
  • 1 location
Intravenous Gammaglobulin for Sickle Cell Pain Crises

The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease. Funding Source: Food and Drug Administration (FDA), Office of Orphan Products Development (OOPD)

thalassemia
narcotics
acute pain
  • 21 views
  • 14 Jun, 2021
  • 1 location
Adipose-derived Mesenchymal Stem Cells in Osteoarthritis

This phase I/II study will enroll 100 subjects with mild to moderate osteoarthritis of the hip/knee/glenohumeral joints will be enrolled according to strict inclusion and exclusion criteria. Subjects will receive a single dose of at least 10 million of autologous Adipose-derived Mesenchymal Stem Cells (ADMCS) every three months for 12 …

  • 0 views
  • 22 Jan, 2021
  • 1 location
Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis

This phase I/II study will enroll 100 subjects with mild to moderate osteoarthritis of the hip/knee/ glenohumeral joint will be enrolled according to strict inclusion and exclusion criteria. Subjects will receive every three months a single dose of at least 10 million of Wharton Jelly derived Mesenchymal Stem Cells (WJMSC) …

  • 0 views
  • 23 Jan, 2021
  • 1 location
Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

The purpose of this study is to determine if prazosin is more effective than placebo in decreasing frequency, severity, disability, and other negative effects of headaches related to mild traumatic brain injury in Service Members and Veterans.

headache
deficit
loss of memory
disoriented
amnesia
  • 49 views
  • 31 Mar, 2021
  • 1 location
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries

One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs. So, evaluation of perfusion of non-vital organ is considered to be adequate measure of patient safety during surgery. Many hypotensive agents such as dexmedetomidine, B blockers, …

postoperative pain
  • 0 views
  • 03 Jun, 2021
  • 1 location