Pain (Pediatric) Clinical Trials

A listing of Pain (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty

This is a prospective, randomized, controlled, open label, parallel four-arm design, multi-center study to compare different intraoperative interventions in the prevention of acute PJI development.

joint reconstruction
avascular necrosis
  • 47 views
  • 14 May, 2021
  • 16 locations
A Study to Evaluate the Pharmacokinetics Safety and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis

This is a study to evaluate pharmacokinetics, safety and tolerability of upadacitinib in pediatric participants with polyarticular course juvenile idiopathic arthritis. This study consists of two parts: Part 1 is multiple-cohort study that consists of two sequential multiple-ascending dose groups. Participants benefiting from the study drug with no ongoing adverse …

swelling
arthritis
methotrexate
  • 95 views
  • 11 Jul, 2021
  • 36 locations
Use of PET/MR Imaging in Chronic Pain

The investigators are studying the ability of PET/MR imaging (using the PET tracer [18F]FDG) to objectively identify and characterize pain generators in patients suffering from chronic pain.

cancer pain
pain disorder
fibromyalgia
nerve damage
chronic pain
  • 562 views
  • 07 Jul, 2021
  • 1 location
A Study of the Safety Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers

This is a randomised, placebo-controlled study of the safety and tolerability of single doses of MEDI0618 in healthy volunteer subjects.

  • 55 views
  • 01 Aug, 2021
  • 2 locations
Peppermint Oil Pharmacokinetics/Dynamics

In children 7-12 years of age with functional abdominal pain (n=42) determine: Aim 1 - To examine and characterize the threshold of the exposure (PK) vs. response (PD) relationship of PMO (menthol) Aim 2 - PD of PMO as assessed by: Microbiome composition (16S RNA sequencing) Transit rate/contractile activity (using …

anxiety
functional abdominal pain
  • 25 views
  • 26 Jan, 2021
Efficacy of Percutaneous SPG Block in Aneurysmal SAH

Researchers are trying to develop alternative means to help patients with headache pain secondary to aneurysmal subarachnoid hemorrhage (bleeding about the brain).

dexamethasone
headache
bupivacaine
subarachnoid hemorrhage
aneurysmal subarachnoid hemorrhage
  • 0 views
  • 15 Feb, 2021
  • 1 location
Cannabidiol Morphine Pain

The purpose of the proposed study is to investigate the interaction of cannabidiol (CBD) and morphine effects on pain sensitivity. Cannabidiol is a cannabinoid (similar to cannabis, or marijuana) present in marijuana that alters some of the effects of marijuana.

oral morphine
morphine
opioid
  • 666 views
  • 11 Jul, 2021
  • 1 location
Safety and Efficacy of XT-150 for Treatment of Neuropathic Pain

Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Neuropathic Pain. Intrathecally administered, single injection.

  • 0 views
  • 01 Aug, 2021
  • 1 location
Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-liability effects of a sub-threshold dose of a commonly used analgesic.

narcotic use
opioid use
oxycodone
drug abuse
prescription drugs
  • 33 views
  • 30 Apr, 2021
  • 1 location
Trichomylin Safety Tolerability and Pharmacokinetics in Healthy Adults and First in Human Osteoarthritis Pain Evaluation

This is a first in human, randomized, double blind, SAD (with food effect) followed by a MAD study of Trichomylin conducted in healthy adult participants.

  • 0 views
  • 19 Jun, 2021
  • 1 location