Pain (Pediatric) Clinical Trials

A listing of Pain (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 110 clinical trials
Evaluation of Post-PACU Pain Management Experiences in Pediatric Ambulatory Surgery Patients

This study aims to assess the differences in overall pain severity, pain management, and satisfaction during recovery period between two groups of children who either receive or do not receive additional education related to expectation and management of postoperative pain.

pain relieving
Accepts healthy volunteers
analgesia
postoperative pain
  • 11 views
  • 22 Oct, 2022
  • 1 location
A Phase 3 Multicenter Study to Evaluate the Long-Term Safety and Efficacy of Baricitinib in Patients From 1 Year to <18 Years of Age With Juvenile Idiopathic Arthritis (JIA) (JUVE-X)

The reason for this study is to see if the study drug baricitinib is safe and effective in the treatment of JIA in participants ages 1 to 17. This study is for participants that have been enrolled in studies I4V-MC-JAHV (NCT03773978) or I4V-MC-JAHU.

arthritis
  • 73 views
  • 21 Oct, 2022
  • 105 locations
An Open-label, Sequential, Ascending, Repeated Dose-finding Study of Sarilumab, Administered With Subcutaneous (SC) Injection, in Children and Adolescents, Aged 1 to 17 Years, With Systemic Juvenile Idiopathic Arthritis (sJIA), Followed by an Extension Phase

Primary Objective: To describe the pharmacokinetic (PK) profile of sarilumab in patients aged 1-17 years with Systemic Juvenile Idiopathic Arthritis (sJIA) in order to identify the dose and regimen for adequate treatment of this population. Secondary Objective: To describe the pharmacodynamics (PD) profile, the efficacy, and the long term safety …

biologics
glucocorticoids
arthritis
anti-rheumatic drugs
rheumatism
  • 112 views
  • 23 Oct, 2022
  • 27 locations
Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)

The long-term objective is to reduce overall low back pain (LBP) burden by testing scalable, first-line, non-pharmacologic strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to chronic back pain. The US is in the midst of an unprecedented pain management crisis. LBP is the most common …

analgesics
back pain
manipulative therapy
manipulation
chronic pain
  • 651 views
  • 04 Oct, 2022
  • 2 locations
An Open-Label Multiple-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis

This is a study to evaluate pharmacokinetics, safety and tolerability of upadacitinib in pediatric participants with polyarticular course juvenile idiopathic arthritis. This study consists of three parts: Part 1 is multiple-cohort study that consists of two sequential multiple dose groups. Participants benefiting from the study drug with no ongoing adverse …

arthritis
methotrexate
swelling
  • 96 views
  • 25 Oct, 2022
  • 16 locations
A LONG-TERM, OPEN-LABEL FOLLOW-UP STUDY OF TOFACITINIB FOR TREATMENT OF JUVENILE IDIOPATHIC ARTHRITIS (JIA)

Evaluate long-term safety and tolerability of tofacitinib in patients with JIA, who have previously participated in tofacitinib JIA studies.

arthritis
treatment regimen
DMARD
  • 319 views
  • 28 Oct, 2022
  • 37 locations
Optimize Low Back Pain (OPTIMIZE)

The objective of this study is to improve health care for patients with chronic LBP and increase the likelihood that patients obtain outcomes that matter most to them. The investigators will accomplish our goal using a sequential multiple randomization (SMART) design comparing the effectiveness of Phase 1 (PT v. CBT) …

combinations
back pain
manual therapy
low back pain
cognitive therapy
  • 537 views
  • 07 Oct, 2022
  • 3 locations
SMART Stepped Care Management for Low Back Pain in the Military Health System (SMART LBP)

This study will be sequential, randomization trial where patients with chronic low back pain are initially randomized to receive 1 of 2 treatments (physical therapy OR Move 2 Health). This will be Phase I of the study intervention. Patients who do not respond to treatment after 6 weeks will undergo …

pain relieving
analgesia
back pain
lumbar disc herniation
low back pain
  • 178 views
  • 04 Oct, 2022
  • 4 locations
Coronary Computed Tomographic Angiography in Intermediate-risk Chest Pain Patients

The aim is to determine whether a diagnostic strategy including early coronary computed tomographic angiography in intermediate-risk patients presenting to the Emergency Department with chest pain reduces the composite endpoint of death, readmission because of myocardial infarction or unstable angina requiring revascularization.

artery disease
infarction
angiography
revascularisation
computed tomography angiography
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design. The three trials are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the …

depressed mood
headache
codeine
chronic pain
fibromyalgia
  • 299 views
  • 04 Oct, 2022
  • 10 locations