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Esophageal Disorders Clinical Trials

A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (78) clinical trials

This study will evaluate the safety and effectiveness of an investigational medication in reducing high levels of eosinophils in the blood and in the tissue of the digestive tract, and improving symptoms in people with EG and/or EGE.  

Phase N/A

Safety and Efficacy of the Swallow Expansion Device (SED) for Improvement of Swallowing in Patients

The purpose of this study is to evaluate if the SED can safely and effectively improve swallowing. Many people with severe swallowing disability (dysphagia) cannot open their upper esophageal sphincter, which is a circular band of muscle that acts like a valve, allowing food to enter the esophagus (food pipe) ...

Phase N/A

Feasibility Study of Biofeedback in Dysphagia Therapy Post Stroke

This study will investigate the feasibility of delivering swallowing therapy using surface electromyography as a means of biofeedback to patients with dysphagia in the acute stroke setting. It will investigate trends in efficacy by comparing biofeedback therapy to usual care. The results will inform future dosing and efficacy studies.

Phase N/A

MRI to Assess the Effect of Non-selective Beta-blocker in Patients With Cirrhosis

Background Standardization and new therapeutic treatments of variceal bleeding has significantly reduced the mortality the last 25 years, but there is still a high 6-week mortality around 15-20% and 1-year mortality of about 40%. Cirrhotic patients without prophylactic treatment suffer a risk of 60% of re-bleeding within the first year ...

Phase N/A

Mechanisms and Management of Infant Dysphagia

Infants with chronic feeding difficulties exhibit inadequacy of suck-swallow and breathe coordination, regurgitation or vomiting, gastroesophageal reflux disease, and airway aspiration. Often these infants must rely on feeding tubes, either inserted through the nose or surgically placed, to meet their nutrition and hydration needs until they are able to orally ...

Phase N/A

Anesthetic to Reduce Dysphagia After Anterior Cervical Discectomy and Fusion Surgery

The patients will be randomly assigned into one of the two groups to receive either bupivacaine hydrochloride 0.5% solution if they are randomized to the treatment group or 0.9% NaCl solution if they are randomized to the control group. These solutions will be poured into the retropharyngeal space intraoperatively before ...

Phase N/A

Design and Implementation of a Nutritional Intervention in Patients With Oropharyngeal Dysphagia

Oropharyngeal Dysphagia causes complications that compromise the efficacy and security of deglutition. An inefficacy deglutition increases the risk of malnutrition and/or dehydration. On the other hand, unsafe deglutition requires more time to complete the oral preparation of the bolus, which can leave residues in the mouth that can then lead ...

Phase N/A

The Effect of Beta-blockers in Substance P Levels and the Swallowing Function

A non-randomised, prospective study to assess the effects of beta-blockers on substance P levels and the swallowing function. The study is going to be carry out in the Gastrointestinal Physiology Laboratory of the Hospital de Matar (Spain). All participants will be actively recruited from a Linked hospital and primary care ...

Phase N/A

The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry

The purpose of this study is to create a registry (collect data and keep it in a research database) to learn more about two methods of taking small tissue samples from your esophagus (the esophagus is the tube that carries food and liquid from your mouth to your stomach.). The ...

Phase N/A

Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma

Patients are enrolled prospectively at the department of Otorhinolaryngology, Head and Neck Surgery & Audiology at Copenhagen University Hospital, Rigshospitalet. All eligible patients with histologically verified squamous cell carcinoma of the oropharynx, regardless of treatment option (as long as the intent is curative) can be included. Outcome measures are assessed ...

Phase N/A