Esophageal Disorders Clinical Trials

A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 45 clinical trials
A Study to Assess DF6002 (BMS-986415) Alone and in Combination With Nivolumab in Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 (BMS-986415) alone and in combination with Nivolumab in participants with advanced solid tumors.

squamous cell carcinoma of head and neck
cytokine therapy
estrogen
carcinoma in situ
pd-l1
  • 22 views
  • 10 Aug, 2022
  • 33 locations
Study of ASP0739 Alone and With Pembrolizumab in Advanced Solid Tumors With NY-ESO-1 Expression Participants

The purpose of this study is to evaluate the safety, and tolerability of ASP0739, when administered as a single agent and in combination with pembrolizumab. This study will also evaluate the clinical response and other measures of anticancer activity of ASP0739 when administered as a single agent and in combination …

intraperitoneal chemotherapy
measurable disease
ny-eso-1
combination therapy
pembrolizumab
  • 0 views
  • 10 Aug, 2022
  • 5 locations
Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

This phase II trial studies how well radiation therapy works for the treatment of gastrointestinal cancer that are spreading to other places in the body (metastatic). Radiation therapy uses high energy x-rays to kill cancer cells and shrink tumors. This trial is being done to determine if giving radiation therapy …

nausea
metastasis
gastrointestinal cancer
neutrophil count
  • 0 views
  • 09 Aug, 2022
  • 1 location
A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate

This is a Phase I, single-center, double blind, placebo-controlled, parallel-group, randomized study designed to evaluate the PK, cardiodynamic ECG effects, safety, and tolerability of 2 single ascending oral doses of linaprazan glurate. The study will explore the PK properties of linaprazan glurate and linaprazan as well as the cardiodynamic ECG …

Accepts healthy volunteers
  • 0 views
  • 10 Aug, 2022
  • 1 location
Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer

> Camrelizumab, a PD-1 inhibitor produced by Hengrui, has been approved for the treatment of various malignant tumors including advanced lung cancer, advanced liver cancer and advanced esophageal cancer. Shows

endocrine therapy
carboplatin
triple negative breast cancer
erbb2
mammogram
  • 0 views
  • 11 Aug, 2022
  • 1 location
Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors.

A phase 1, open-label, dose escalation and expansion study of PF-07062119 in patients with selected advanced or metastatic gastrointestinal tumors

colorectal adenocarcinoma
measurable disease
adenocarcinoma
  • 33 views
  • 10 Aug, 2022
  • 15 locations
Single Dose Escalation of PHIN-214 in Child-Pugh A Liver Cirrhotics

This single ascending dose (SAD) study evaluates PHIN-214, being studied to determine the safety, tolerability, and pharmacokinetics, and establish the maximum tolerated dose of this compound in patients with compensated cirrhosis.

fibroscan
body mass index
terlipressin
  • 0 views
  • 11 Aug, 2022
  • 1 location
Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions

Gastrointestinal stromal tumors (GIST) are the most common malignant subepithelial lesions (SELs) found in the gastrointestinal tract. The diagnosis and differentiation of these lesions from other subepithelial hypoechogenic tumors (i.e.as leiomyoma), is important as this may have an impact in the prognosis and treatment of either. Due to GIST's notable …

leiomyoma
  • 0 views
  • 11 Aug, 2022
  • 1 location
Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity

Patients enrolled in the study will receive standard of care adjuvant or definitive breast, chest wall or thoracic radiation therapy.Cardiac mitochondrial dysfunction is a hallmark of radiation-induced cardiac injury. Reactive oxygen species (ROS) produced by ionizing radiation cause oxidation of mitochondrial proteins and alter oxidative phosphorylation and pyruvate metabolism(5). The …

estradiol
  • 0 views
  • 09 Aug, 2022
  • 1 location
Reducing Pain During Orogastric Tube Placement in Preterm

The aim of this study is to determine the effectiveness of 3 different methods (breast milk pacifier, sucrose pacifier and pacifier) in reducing pain caused by Orogastric Tube (OGT) insertion in preterm newborns by monitoring behavioral and physiological changes in infants. The study was planned as a randomized controlled experimental …

opioid
Accepts healthy volunteers
analgesics
  • 0 views
  • 11 Aug, 2022
  • 2 locations