Esophageal Disorders Clinical Trials

A listing of Esophageal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 45 clinical trials
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

percentage of patients experiencing an objective response in the setting of advanced unresectable or metastatic esophageal squamous cell carcinoma (ESCC). Sub study 02 - Cohort B1, B2 and B3 would

cancer
squamous cell carcinoma
cetuximab
pembrolizumab
carcinoma
  • 5 views
  • 05 Aug, 2022
  • 36 locations
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies

This clinical trial is evaluating a drug called BT8009 alone and in combination with nivolumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The main goals of this study are to: Find the recommended dose of BT8009 …

targeted therapy
cancer of the ovary
breast cancer
triple negative breast cancer
mammogram
  • 109 views
  • 09 Aug, 2022
  • 19 locations
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors

This trial will study ladiratuzumab vedotin (LV) to find out if it works to treat different types of solid tumors. It will also find out what side effects may occur. A side effect is anything the drug does besides treating cancer.

chemoradiotherapy
erbb2
systemic therapy
metastasis
chemotherapy regimen
  • 13 views
  • 09 Aug, 2022
  • 64 locations
MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of pembrolizumab/vibostolimab co-formulation (MK-7684A) with or without other anticancer therapies in participants with selected advanced solid tumors. The primary hypothesis is that pembrolizumab/vibostolimab co-formulation is superior to pembrolizumab alone in terms of objective response rate or …

adenocarcinoma
cancer of the ovary
oxaliplatin
mammogram
fluorouracil
  • 1 views
  • 12 Aug, 2022
  • 64 locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

platelet count
mammogram
sapanisertib
potassium
dasatinib
  • 6575 views
  • 08 Aug, 2022
  • 909 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

salivary glands (closed to accrual 03/20/2018) Salivary gland type tumors of head and neck, lip, esophagus, stomach, trachea and lung, breast and other location (closed to accrual)

ACTH
vasectomy
bone scan
cancer of the ovary
immunosuppressive agents
  • 6634 views
  • 10 Aug, 2022
  • 752 locations
Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

This phase II trial studies the side effects and best dose of propranolol when administered concurrently with SOC neoadjuvant CRT in patients with esophageal carcinoma, with a safety lead-in and

  • 0 views
  • 10 Aug, 2022
  • 1 location
NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

of patients with esophageal adenocarcinoma. NBTXR3 is a drug that when activated by radiation therapy, may cause targeted destruction of cancer cells. Radiation therapy uses high energy x-rays to

  • 0 views
  • 12 Aug, 2022
  • 1 location
Follow-up After a Stay in Intensive Rehabilitation for Patients With Swallowing Disorders (E-CRIL)

Prospective, open-label, randomized, single-center study evaluating the benefit of a months long monthly telephone follow-up for patients with chronic disorders following the after-effects of anti-cancer treatments after an intensive rehabilitation stay versus standard follow-up.

  • 0 views
  • 10 Aug, 2022
  • 1 location
Clinical Trial for Clinical Excellence and Safety Evaluation of 4-channel Functional Electric Stimulator

This study is a pilot study to prepare clinical trials to evaluate the safety and effectiveness of 4-channel electric stimulation therapy devices as a newly developed function for the treatment of dysphagia disorders. The purpose of this study is to investigate the difference in effect by the electric stimulation method …

Accepts healthy volunteers
  • 0 views
  • 11 Aug, 2022
  • 1 location