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Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (192) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT01794000?term=H7T-MC-TADO&rank=1

Phase N/A

People with Sickle Cell Anemia are asked to participate in a research study being conducted by Montefiore Medical Center.    Clinicaltrials.gov: NCT03264989

Phase N/A

This is an experimental research study and does not constitute treatment or therapy. INCB059872 is an investigational drug that is being studied by Incyte Corporation (the “Sponsor” of the research study) for use in the treatment of Sickle Cell Disease.     INCB059872 is a compound in the family of medications ...

Phase

Chronic leg ulcers are a serious complication of Sickle Cell Disease, in which red blood cells break down earlier than normal and can stick to vessel walls, causing a blockage that slows or stops the flow of blood. Current therapies are not very effective and often leg ulcers take months ...

Phase

The purpose of the study is to Evaluate the Effect of Ticagrelor versus Placebo in Reducing the Rate of Vaso-Occlusive Crises in Pediatric Patients with Sickle Cell Disease

Phase

Nonmyeloablative allogeneic peripheral blood stem cell (PBSC) transplants are currently being investigated in phase I/II trials assessing engraftment, efficacy, and toxicity at a number of transplant centers. Our ongoing protocol for patients with severe congenital anemias, particularly sickle cell disease (SCD), and an HLA-matched sibling donor has had excellent preliminary ...

Phase N/A

Polymerization of deoxy-sickle-hemoglobin (deoxy-HbS), the root cause of sickle cell disease (SCD) is influenced by a few factors, a key factor is 2,3-diphosphoglycerate (2,3-DPG) concentration in the red blood cells. 2,3-DPG is an allosteric effector on hemoglobin oxygen binding with a greater binding affinity to deoxygenated hemoglobin than to oxygenated ...

Phase

Children with sickle cell disease are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

The STRONG SCD study is being conducted to help advance research into an oral investigational drug for people with sickle cell disease (SCD). It is evaluating the investigational drug—compared to placebo (looks like the investigational drug but does not contain any active ingredient)—to understand how it affects people with SCD ...

Phase

People with sickle cell disease are asked to participate in a research study being conducted by Montefiore Medical Center.  

Phase N/A