Crohn's Disease (Pediatric) Clinical Trials

A listing of Crohn's Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 121 clinical trials
Diet Intervention for Crohn's Disease Patient

The purpose of this study is to determine the effectiveness of a low-fat, high fiber diet (LFD) containing a minimal proportion of fat to improve gastrointestinal symptoms, quality of life and signs of inflammation in blood and stool.

corticosteroids
antibiotics
ulcerative colitis
antibiotic therapy
Accepts healthy volunteers
  • 0 views
  • 10 Dec, 2021
  • 1 location
A Dietary Intervention Study on the Microbiome in Crohn's Disease Patients

This protocol is designed to compare the effectiveness of a soy-based diet or identical diet without soy given to patients with Crohn's disease (CD) in remission, patients with active CD, or healthy controls. The assigned diet will be compared to participant 'baseline' (pre-diet) in terms of its ability to change …

infliximab
adalimumab
remission
corticosteroids
natalizumab
  • 0 views
  • 21 Jul, 2022
  • 1 location
USTekinumab in Fistulising Perianal Crohn's Disease (USTAP) (USTAP)

Phase IV Trial design : Multicentre, randomized, double-blind, placebo-controlled study Population : Moderate to severe Crohn's disease with at least one active perianal fistula track Investigational treatment : Group 1: Ustekinumab (UST) IntraVenous (IV) induction (6mg/kg) followed by UST SubCutaneous (SC) 90mg every 8 weeks. Group 2: Placebo IV followed …

perianal crohn's disease
anti-tnf therapy
ustekinumab
azathioprine
crohn's disease
  • 2 views
  • 29 May, 2022
  • 5 locations
Stem Cell Transplantation in Crohn's Disease

Unfortunately, some patients with Crohn's disease (CD) fail to respond to the best clinical treatments and some only experience temporary benefit. For severe Crohn's disease, there is an experimental treatment called "high dose immunoablation" followed by autologous hematopoietic stem cell transplantation (HSCT). This study removes over active lymphocytes (immunoablation) and …

stem cell transplantation
crohn's disease
cyclophosphamide
  • 0 views
  • 13 Apr, 2022
  • 1 location
"Tasty&Healthy" Dietary Approach for Crohn's Disease

Despite the advent of multiple novel medications, many patients with Crohn's disease (CD) fail to achieve mucosal healing (MH). Exclusive enteral nutrition (EEN) has been shown to induce clinical remission accompanied by MH in many of CD patients. The aim of this proposal is to explore the effectiveness of the …

remission
immunomodulators
faecal calprotectin
maintenance treatment
enteral nutrition
  • 0 views
  • 03 Jun, 2021
  • 1 location
Flagyl Microbiome in Crohn's Disease

This study will compare the types of bacteria in the colon before and after colon resection surgery. The investigator will also compare standard post-operative antibiotic treatment to flagyl (metronidazole) treatment post-operatively to see if giving the antibiotic, decreases the incidence of return of Crohn's disease.

crohn's disease
antibiotics
  • 0 views
  • 01 Nov, 2021
  • 1 location
Microbiome Modification to Enhance Stelara Response in Crohn's Disease (MIM-TESRIC)

This pilot study is being completed to determine whether a low-serine diet vs a high serine diet will reduce inflammation and symptoms in Crohn's disease (CD), as well as determine whether a low-serine diet (vs. a high serine diet) will improve responses in patients initiating therapy with Ustekinumab (Stelara), an …

ustekinumab
prednisone
crohn's disease
  • 0 views
  • 03 Jun, 2022
  • 1 location
A Comparative Study of MRI, US and CE for Assessing Treatment Response in Known Crohn's Disease

The aim of this study is to evaluate non-invasive imaging techniques for assessing treatment response in known Crohn's disease. Comparing imaging modalities: The applicability of small bowel colon capsule endoscopy (SBCCE), magnetic resonance enterocolonography (MREC) and ultrasound (US) for diagnosing ulcer healing after medical treatment in patients with symptomatic Crohn's …

corticosteroids
ulceration
endoscopy
crohn's disease
capsule endoscopy
  • 5 views
  • 26 Feb, 2022
  • 1 location
Autologous Stem Cell Transplantation for Crohn's Disease

The objective of this study is to evaluate the safety and effectiveness of administering high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells (PBSC) in pediatric and adult patients with severe Crohn's disease.

adalimumab
corticosteroids
natalizumab
cyclophosphamide
ustekinumab
  • 168 views
  • 21 Mar, 2022
  • 2 locations
A Study to Evaluate the Safety of ALLO-ASC-CD for Treatment of Crohn's Disease

This is a phase I study to evaluate the safety of ALLO-ASC-CD for the treatment of crohn' disease. ALLO-ASC-CD is intravenous infusion containing allogenic adipose-derived mesenchymal stem cells.

immunosuppressive agents
tumor necrosis factor alpha
ulceration
tumor necrosis factor
conventional treatment
  • 0 views
  • 26 Jan, 2022
  • 1 location