Crohn's Disease (Pediatric) Clinical Trials

A listing of Crohn's Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 121 clinical trials
The CURE - CD Trial

A prospective randomized three-arms controlled trial of Crohn's Disease (CD) patients in remission of <24 months duration. Patients will undergo screening by Magnetic Resonance Enterography (MRE) and patency capsule, and (if agreeing by separate consent) a baseline colonoscopy. Patients in whom patency of small bowel is proven will undergo video-capsule …

remission
capsule endoscopy
endoscopy
enteropathy
  • 7 views
  • 05 Mar, 2022
  • 1 location
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's Colitis

Crohn's disease has several phenotypes (inflammatory, stricturing, fistulizing) and location (small bowel, ileocecal, colon, and perianal). Approximately one third of patients have inflammation limited to the colon. Up to two thirds will become medically refractory and require a total abdominal colectomy for symptom control. The purpose of this study is …

methotrexate
monoclonal antibodies
thiopurines
corticosteroids
anti-tnf therapy
  • 0 views
  • 19 Apr, 2022
  • 1 location
Effect of the Exclusive Enteral Nutrition Combined With Azathioprine for Remission of Crohn's Diseases After Surgery

for some patients with Crohn's diseases undergoing surgery,whether exclusive enteral nutrition(EEN) could delay the disease relapse needs exploration.The trial will study whether the efficacy of postoperative EEN could help keeping remission.

remission
bowel resection
enteral nutrition
azathioprine
  • 1 views
  • 15 Mar, 2022
  • 1 location
The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )

The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relapses) and the quality of life, including levels of physical activity, in children diagnosed Crohn's disease (CD).

crohn's disease
adalimumab
abdominal pain
vitamin
pediatric onset crohn's disease
  • 139 views
  • 26 Jan, 2021
  • 7 locations
MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES) (SPARES)

Study description - Patients will be randomized according to post-operative recurrence risk to either a high ligation of ileocolic artery or mesenteric sparing ileocolic resection for terminal ileal Crohn's disease. The primary endpoint 6-month endoscopic recurrence. Endpoints - Primary endpoint; 6 months Secondary endpoints at 1 and 5 years post …

crohn's disease
ustekinumab
thiopurines
corticosteroids
antibiotics
  • 8 views
  • 19 Apr, 2022
  • 6 locations
A Phase 2 Clinical Trial: Xanthohumol Metabolism and Signature (XMaS) in Crohn's Disease

A pilot study to assess the safety and tolerability of an orally administered natural product derived from hops, called xanthohumol, in humans with Crohn's Disease, in order to identify a biological signature of xanthohumol exposure, and to characterize the role of xanthohumol metabolism by intestinal microorganisms in that signature within …

remission
crohn's disease
  • 48 views
  • 30 May, 2021
  • 1 location
The Intensive Post Exclusive Enteral Nutrition Study

Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms. Exclusive enteral nutrition (EEN), a liquid only diet without allowance of any extra food, is the main treatment for children with active CD. However, when children stop the …

crohn's disease
enteral nutrition
  • 0 views
  • 24 Jan, 2021
  • 5 locations
Interest of the Dosage of Adalimumab Serum Levels in Crohn's Disease Patients for Prevention of Postoperative Recurrence (ADAPT)

Study comparing 2 modalities of Crohn's disease patients postoperative follow-up treated with adalimumab (Humira or biosimilar) : immunomonitoring of adalimumab serum levels versus standard follow-up, which is based on the clinical and biological activity of the disease.

biosimilar
tumor necrosis factor
crohn's disease
adalimumab
humira
  • 2 views
  • 26 Feb, 2022
  • 1 location
The Impact of Time Restricted Feeding in Crohn's Disease (TRF-CD)

Time-restricted feeding (TRF) is a dietary regimen involving the consumption of food and liquids within a defined time window with or without additional restriction on dietary composition. TRF has been associated with improvements in inflammation, host metabolism, autophagy, gut microbial composition, and gut permeability. Crohn's disease is an inflammatory bowel …

inflammatory bowel disease
enteropathy
crohn's disease
ileal disease
faecal calprotectin
  • 11 views
  • 22 Mar, 2022
  • 1 location
Loss of RESponse to Ustekinumab Treated by Dose Escalation (REScUE)

The aim of the study is to investigate the effect of re-induction with ustekinumab ≈6mg/kg IV followed by two different maintenance dosing regimens 90 mg subcutaneous every 8 weeks (Q8W) vs 90 mg subcutaneous every 4 weeks(Q4W) on clinical, biological and pharmacological outcomes in patients with Crohn's disease who show …

abdominal pain
ulceration
crohn's disease
ileitis
ustekinumab
  • 3 views
  • 12 Mar, 2022
  • 1 location