Crohn's Disease (Pediatric) Clinical Trials

A listing of Crohn's Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 121 clinical trials
A Multicenter, Randomized, Double-Blind, Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn's Disease (CULTIVATE)

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, …

crohn's disease
biosimilar
certolizumab pegol
immunosuppressive agents
ustekinumab
  • 207 views
  • 20 Sep, 2022
  • 323 locations
A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is an extension study to evaluate safety and efficacy of ozanimod in participants with moderately to severely active Crohn's Disease.

remission
crohn's disease
  • 1128 views
  • 22 Sep, 2022
  • 492 locations
A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula (EMPIRE)

The main aim is to check the long term side effects of a repeat treatment of darvadstrocel and to see if that treatment improves symptoms of Crohn's disease and complex perianal fistula. Participants will attend 8 clinic visits and will receive 1 treatment of darvadstrocel at the third visit. A …

remission
crohn's disease
  • 0 views
  • 06 Mar, 2022
  • 27 locations
An Investigational Study of Experimental Medication BMS-986165 in Participants With Moderate to Severe Crohn's Disease

The purpose of this study is to assess the safety and effectiveness of BMS-986165 compared to placebo in participants with moderately to severely active Crohn's Disease.

enteropathy
crohn's disease
  • 372 views
  • 11 Jul, 2022
  • 216 locations
Stopping Aminosalicylate Therapy in Inactive Crohn's Disease (STATIC)

The purpose of this study is to assess whether withdrawal of aminosalicylate (5-ASA) is non-inferior to continuation of 5-ASA therapy in Crohn's disease (CD) subjects in remission.

mesalamine
remission
crohn's disease
aminosalicylate
  • 146 views
  • 04 Mar, 2022
  • 28 locations
Anastomotic Leakage and Value Of Indocyanine Green in Decreasing Leakage Rates

Anastomotic leakage (AL) is one of the major complications after gastrointestinal surgery. Compromised tissue perfusion at the anastomosis site increases the risk of AL. Indocyanine green (ICG) combined with fluorescent near infrared imaging has proven to be a feasible and reproducible application for real-time intraoperative quantification of the tissue perfusion …

  • 0 views
  • 03 Feb, 2021
  • 1 location
ENhanced Recovery in CHildren Undergoing Surgery (ENRICH-US)

The institution of perioperative Enhanced Recovery Protocols (ERPs) has been found to decrease hospital length of stay, in-hospital costs, and complications among adult surgical populations but data in pediatric populations are lacking. The Assessing Effectiveness and Implementation of a Perioperative Enhanced Recovery Protocol for Children Undergoing Gastrointestinal Surgery, which has …

ulcerative colitis
abdominal surgery
crohn's disease
inflammatory bowel disease
enteropathy
  • 0 views
  • 12 May, 2022
  • 1 location
A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In) (INTREPID)

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

methotrexate
crohn's disease
conventional treatment
mercaptopurine
antibiotics
  • 550 views
  • 14 Sep, 2022
  • 77 locations
Clinical Database of Colorectal Robotic Surgery (ROBOT CR)

Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.

ulcerative colitis
crohn's disease
low anterior resection
colitis
colectomy
  • 1 views
  • 12 Feb, 2022
  • 4 locations
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

covid-19
Accepts healthy volunteers
medical marijuana
disease or disorder
brimonidine tartrate ophthalmic solution
  • 15119 views
  • 13 Jun, 2022
  • 16 locations