Crohn's Disease (Pediatric) Clinical Trials

A listing of Crohn's Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 27 clinical trials
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VIVID-1, a clinical research study for adults 18–80 with moderately to severely active Crohn’s disease.

A phase 3 research study of an injectable investigational medicine for adults ages 18 to 80 with moderate to severe Crohn’s disease. Note that study participants may receive the investigational medication, a currently approved Crohn’s medication, or placebo. The study comprises four periods: screening, treatment period 1, treatment period 2, …

gastrointestinal disorder
inflammatory bowel disease
gastrointestinal diseases
crohn's disease
  • 66 views
  • 20 Jul, 2021
  • 74 locations
Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease

The objectives of this study are to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06651600 (200 mg for 8 weeks followed by 50 mg for 4 weeks) dosed once daily and PF-06700841 (60 mg for 12 weeks) dosed once daily during an induction period of 12 weeks, followed …

antibiotics
vedolizumab
mesalamine
adalimumab
ustekinumab
  • 1364 views
  • 01 Aug, 2021
  • 299 locations
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

ileitis
fistulising crohn's disease
endoscopy
ustekinumab
colitis
  • 792 views
  • 19 Jul, 2021
  • 800 locations
A Study of E6011 in Participants With Active Crohn's Disease

The primary purpose of this study is to examine the efficacy and safety of E6011 at 12 weeks after administration by means of double-blind placebo-controlled trial.

ciprofloxacin
antibiotics
sulfasalazine
corticosteroids
methotrexate
  • 21 views
  • 26 Jul, 2021
  • 76 locations
A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease

This is a study in adults with Crohn's Disease who also have fistulas near the anus. The study has 2 parts. The first part is to find out more about what causes the fistulas. In this part of the study, tissue samples are taken from patients. The second part of …

antibiotics
thiopurines
fistulising crohn's disease
vedolizumab
bowel resection
  • 13 views
  • 21 Jul, 2021
  • 19 locations
Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. This study will evaluate how well risankizumab works compared to ustekinumab. This study will assess change in Crohn's Disease Activity Index (CDAI). Risankizumab is an investigational drug being developed for the treatment of …

abdominal pain
risankizumab
tumor necrosis factor
tumour necrosis
crohn's disease
  • 97 views
  • 01 Aug, 2021
  • 437 locations
A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to see if the study drug mirikizumab is safe and effective in participants with moderately to severely active Crohn's disease.

crohn's disease
ustekinumab
  • 646 views
  • 25 Jul, 2021
  • 992 locations
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, …

vedolizumab
adalimumab
ustekinumab
immunosuppressive agents
mercaptopurine
  • 63 views
  • 22 Jul, 2021
  • 158 locations
TAK-018 for Prevention of the Recurrence of Postoperative Crohn's Disease (CD)

The purpose of this study is to evaluate the efficacy of TAK-018 in reducing endoscopic recurrence of intestinal inflammation in postoperative participants with CD after a planned laparoscopic ileocecal resection with primary anastomosis.

antibiotics
thiopurines
tumor necrosis factor alpha
antibiotic therapy
tumor necrosis factor
  • 10 views
  • 18 Jul, 2021
  • 64 locations
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

The reason for this study is to determine the long-term efficacy and safety of the study drug mirikizumab in participants with Crohn's disease.

crohn's disease
  • 22 views
  • 24 Jul, 2021
  • 302 locations