Neuroendocrine Carcinoma Clinical Trials

A listing of Neuroendocrine Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 50 clinical trials
Combination Immunotherapy in Rare Cancers Under InvesTigation (MOST-CIRCUIT)

into four groups: Neuroendocrine cancers: Atypical bronchial carcinoid, neuroendocrine carcinoma and Grade 3 NETs independent of primary site (SCLC excluded) Biliary tract

  • 4 views
  • 04 Oct, 2022
  • 10 locations
A Phase 1b/2a, Open Label Study to Evaluate Anti-tumor Efficacy and Safety of rhIL-7-hyFc (NT-I7) in Combination With Anti-PD-L1 (Atezolizumab) in Patients With Anti-PD-1/PD-L1 naïve or Relapsed/Refractory High-risk Skin Cancers

The purpose of this study is to test whether the addition of NT-I7 to atezolizumab provides clinically meaningful outcomes for patients with anti-PD-1/PD-L1 naive or relapsed/refractory high-risk melanoma, Merkel Cell Carcinoma (MCC) and cutaneous Squamous Cell Carcinoma (cSCC)

pd-l1
carcinoma
metastatic melanoma
merkel cell carcinoma
squamous cell carcinoma
  • 14 views
  • 10 Oct, 2022
  • 7 locations
Exercise to Boost Response to Checkpoint Blockade Immunotherapy

30 minutes of moderate exercise on an arm ergometer, a cycle ergometer, or a treadmill prior to each administration of standard of care checkpoint blockade immunotherapy across all cycles

nivolumab
pembrolizumab
immunomodulator
carcinoma
immunologic adjuvant
  • 0 views
  • 10 Oct, 2022
  • 1 location
EMERGE-201: A Phase 2, Multicenter, Open-label Study of Lurbinectedin Efficacy and Safety in Participants With Advanced or Metastatic Solid Tumors (EMERGE-201)

This is an open-label, multicenter, phase 2 study of lurbinectedin monotherapy in participants with advanced (metastatic and/or unresectable) solid tumors.

  • 0 views
  • 18 Oct, 2022
  • 12 locations
Immunotherapy Adjuvant Trial in Patients With Stage I-III Merkel Cell Carcinoma (I-MAT)

The I-MAT trial is a randomised, placebo-controlled, phase II trial of adjuvant Avelumab in patients with stage I-III Merkel cell carcinoma aiming to explore the efficacy of avelumab as adjuvant immunotherapy.

metastasis
immunomodulator
carcinoma
18f-fdg
positron emission tomography
  • 6 views
  • 07 Oct, 2022
  • 17 locations
A First-in-Human, Phase 1/2, Dose Escalation Study of BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors

This is a first-in-human (FIH), Phase 1, open-label, multicenter study to assess safety and determine the recommended Phase 2 dose (RP2D) of BOXR1030 administration after lymphodepleting chemotherapy (LD chemotherapy) in subjects with glypican-3 positive (GPC3+) advanced solid tumors.

ejection fraction
small molecule
squamous cell carcinoma
systemic therapy
mitomycin c
  • 0 views
  • 23 Oct, 2022
  • 1 location
Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

This research study is studying a combination of drugs as a possible treatment for rare genitourinary malignancies among four cohorts, bladder or upper tract carcinoma with variant histology, adrenocortical carcinoma, other rare genitourinary carcinomas and any genitourinary carcinoma with neuroendocrine differentiation. Given preliminary results, the study is being tested in …

platelet count
heparin
nivolumab
carcinoma
tubal ligation
  • 83 views
  • 04 Oct, 2022
  • 6 locations
CMP-001 in Combination With IV PD-1-Blocking Antibody in Subjects With Certain Types of Advanced or Metastatic Cancer

CMP-001-009 is a Phase 2 study of intratumoral CMP-001 in combination with an intravenous PD-1-blocking antibody administered to participants with certain types of advanced or metatastic cancer. The primary objective of the study is to determine the Investigator-assessed confirmed objective response with CMP-001 in combination with a programmed cell death …

cancer
  • 0 views
  • 04 Oct, 2022
  • 14 locations
An Open-Label, Multicenter, Phase 1B/2 Study of RP1 in Solid Organ Transplant Recipients With Advanced Cutaneous Malignancies (ARTACUS)

This Phase 1B/2 study is a multicenter, open-label, study of RP1 to investigate the (a) objective response rate, in addition to (b) safety and tolerability of RP1 for the treatment of advanced cutaneous malignancies in up to 65 evaluable organ transplant recipients. This will include patients with either previous renal, …

organ transplantation
cytotoxic t-lymphocyte antigen 4
carcinoma
formalin-fixed paraffin-embedded
squamous cell carcinoma
  • 22 views
  • 28 Oct, 2022
  • 14 locations
A Study of Erdafitinib in Castration-Resistant Prostate Cancer Patients Evaluating Markers of Bone Remodeling and FGF Signaling in Plasma and Bone Marrow

This phase II trial studies the effect of erdafitinib in treating patients with prostate cancer that grows and continues to spread despite the surgical removal of the testes or drugs to block androgen production (castration-resistant). Erdafitinib may stop the growth of tumor cells by blocking some of the enzymes needed …

  • 0 views
  • 25 Oct, 2022
  • 1 location