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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (79) clinical trials

Post-Marketing Surveillance Study of Fycompa Film-coated Tablets in Korean Patients

The objective of this post-marketing surveillance study is to observe the safety profile of Fycompa film-coated tablets 2/4/6/8/10/12 milligrams (mg) in a normal clinical practice setting.

Phase N/A

Epidemiology Study on Neonatal Seizure

This study is designed to describe the incidence of newborn with uncontrolled seizures. Seizures can be associated with any high-risk factors during perinatal stage and diagnosed by abnormal electrical activity in the brain. In this study researchers will use electroencephalography (EEG) to determine and monitor newborn with uncontrolled or suspected ...

Phase N/A

Biomarker for Creatine Deficiency Syndromes

The creatine deficiency syndromes (CDS) are a group of inborn errors of metabolism which interrupt the biosynthesis or transportation of creatine. Individuals with creatine deficiency syndromes classically present with intellectual disabilities and seizure disorders and may present with pyramidal/extrapyramidal neurologic findings and behavioral problems as well. There are three Cerebral ...

Phase N/A

Is Protein S100B a Predictor of First-to-chronic Seizure Conversion in Adults?

The secondary objectives of this study are to investigate the: Prognostic capacity of serum S100B levels to predict seizure recurrence. B) Association between the variation (%) of serum S100B levels between first seizure episode and scheduled follow-up (D14-D28) and seizure recurrence. Correlation of S100B with IL-1b, IL-6, NSE serum levels ...

Phase N/A

Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

Epilepsy is a disease affecting 1-2% of the population. Currently, the only known cure for epilepsy is surgery, which is much more effective at eliminating seizures arising from the medial temporal lobe compared with the neocortex. The problem with neocortical epilepsy is that the population of neurons underlying each epileptiform ...

Phase N/A

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome

This study addresses the changes in the axonal excitability parameters. It will compare these changes in patients with early infantile epileptic encephalopathy with HCN1 channel mutation and in control patients, with and without epilepsy.

Phase N/A

Pharmacokinetics of Anti-epileptic Drugs in Obese Children

The study is a prospective, multi-center, open-label clinical trial. Study's purpose is to characterize the pharmacokinetics and safety of four oral anti-epileptics drugs (levetiracetam, valproic acid [divalproex sodium ER or immediate release formulation if inadequate enrollment}, topiramate, and oxcarbazepine) in a non-randomized sample of obese children and adolescents. The study's ...

Phase N/A

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Context: Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of specific medication selections or ...

Phase N/A

Prediction of the Cognitive Effects of Electroconvulsive Therapy Via Machine Learning and Neuroimaging

Due to the immense disease burden of major depression and unsatisfactory response to standard pharmacological and psychological treatments, the need for treatment alternatives is evident. Electroconvulsive therapy (ECT) remains to be the most efficacious treatment known for treatment-resistant depression. However, although many studies show response rates above 70%, ECT can ...

Phase N/A

National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug

The main goal of this study is to evaluate the additional value of EEG-fMRI method in the presurgical evaluation of focal intractable epilepsy. To consider a patient for surgery, the main difficulty is to define accurately the epileptogenic zone. This definition is complex and is often supported by several types ...

Phase N/A