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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (364) clinical trials

The Aging Brain ANSWERS Program

The majority of people with Alzheimer's (AD) and Traumatic brain Injury (TBI) are cared for in primary care settings and receive significant amounts of care and assistance in activities of daily living from family members or friends. The ABC ANSWERS intervention will incorporate and integrate the common features of an ...

Phase N/A

Preventing Epilepsy Using Vigabatrin In Infants With Tuberous Sclerosis Complex

The central hypothesis of this Phase IIb trial is that early identification of electroencephalography (EEG) biomarkers and early treatment versus delayed treatment with vigabatrin in infants with tuberous sclerosis complex (TSC) will have a positive impact on developmental outcomes at 24 months of age. It would also prevent or lower ...

Phase

Seizure Rescue Medication: Caregiver Education in a Simulation Setting

The investigators will implement an intervention jointly with a simulation program to determine the most effective training model: verbal instructions, instructional video, or use of a mannequin. Caregivers will undergo a training curriculum, and 60 caregivers (20 assigned to each educational model) will be matched into three groups and assigned ...

Phase N/A

Analysis of Electrocorticographic Signals

There are 2 separate experiments proposed, both of which use repeated-measures designs. Electrocorticography (ECoG) study of visual working memory. Each trial from the behavioral task will start by presenting subjects with two visual images, one each from two of these three categories: faces, words, and outdoor scenes. They will then ...

Phase N/A

Single Neurons Responses During Visual Recognition in Epileptic Patients

In this interventional study, patients explored with mixed intracerebral electrodes (micro and macro-contacts) will be presented sets of images (objects, unknown faces, famous faces). Spikes and Multi-Unit-Activity will be recorded and analyzed and compared between conditions.

Phase N/A

Effects of Green Light Exposure on Epileptic Spikes in Patients With Refractory Epilepsy

The trial is designed to detect (1) change in spike frequency on EEG before and after exposure to low intensity green light, and (2) presence or absence of neurologic/systemic symptoms referable to exposure of the pre-selected duration, intensity, and band of green light. Our primary aim is to determine whether ...

Phase N/A

Defining the Operating Characteristics of NIRS in the Diagnosis of Pediatric Traumatic Intracranial Hemorrhage

Patients that present to Dayton Children's Hospital with a head CT order for suspected TBI will be approached for enrollment. An alert will notify study personnel as CT scans are ordered. The goal is to obtain NIRS data within four-hours before or after the CT scan. Informed consent will be ...

Phase N/A

Towards Comparative Effectiveness in Military Vestibular Rehabilitation

Aim 1. To prospectively evaluate the reliability of a series of diagnostic and outcome assessment tools in a military cohort with post-concussive vestibular symptoms; these to include the Dizziness Handicap Inventory (DHI), Activities-Specific Balance Confidence Scale (ABC), the Computerized Dynamic Posturography (CDP) and the Neuro-Otologic Test System (NOTC). Hypothesis 1. ...

Phase N/A

Strategy Training on Improving Executive Functions in Persons Following Acquired Brain Injury

This proposed study aims to examine the efficacy of a strategy training intervention program on improving executive functions and lessoning disability among community-dwelling people with ABI, and to determine whether the effects of the intervention persist 1 year following the intervention. To address these purposes, a double-blinded, parallel-group randomized controlled ...

Phase N/A

Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy

Patients with drug-refractory epilepsy sometimes need to be implanted with intracerebral electrodes in order to identify their seizure onset zone. During this procedure, direct brain electrical stimulations is a standard clinical practice to assess seizure sensitivity and for functional mapping. However the efficiency of these stimulations can be questioned and ...

Phase N/A