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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (264) clinical trials

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome (Cohort 1) and partial-onset seizures (POS) (Cohort 2).


Youth Epilepsy and Successful Self-Management Intervention

YESS! is a web-based self management program developed to enhance the motivation and skills of youth with epilepsy. This clinical trial uses a pre-test, post-test design where all consenting participants are given access to the intervention.

Phase N/A

Circulating microRNAs as Biomarkers of RESPIratory Dysfunction in Patients With Refractory epilePSY

Sudden and unexpected death in epilepsy (SUDEP) has become a major issue for patients with epilepsy and their physicians. SUDEP is a nontraumatic and non-drowning death in patients with epilepsy, unrelated to a documented status epilepticus, in which postmortem examination does not reveal a toxicologic or anatomic cause of death. ...

Phase N/A

Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients

To investigate the role of KATP channels in migraine with aura patients.

Phase N/A

Diffusion MRI-1 Imaging Database

The purpose of the dMRI-1 data collection study is to establish a database of clinical images and limited medical history information from patients that have previously received a dMRI scan. All data collected will be de-identified. No safety or effectiveness assessments will be completed.

Phase N/A

Mobile Application of Seizure Diary (Brain4U) in Epilepsy Care

We evaluate the general and personal knowledge of epilepsy before and after using mobile application, Brain4U. Brain4U provides seizure diary, brief screening tools for evaluating combined psychiatric problems, alarm to take antiepileptic drugs (AED) regularly on time. Through the Brain4U application, patients or caregivers can record their (or their children's) ...

Phase N/A

Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy

Patients with drug-refractory epilepsy sometimes need to be implanted with intracerebral electrodes in order to identify their seizure onset zone. During this procedure, direct brain electrical stimulations is a standard clinical practice to assess seizure sensitivity and for functional mapping. However the efficiency of these stimulations can be questioned and ...

Phase N/A

Effects of Green Light Exposure on Epileptic Spikes in Patients With Refractory Epilepsy

The trial is designed to detect (1) change in spike frequency on EEG before and after exposure to low intensity green light, and (2) presence or absence of neurologic/systemic symptoms referable to exposure of the pre-selected duration, intensity, and band of green light. Our primary aim is to determine whether ...

Phase N/A

Natural History and Functional Status Study of Patients With Lafora Disease

A natural history and functional status study to characterize the clinical disease course in Lafora disease patients using standardized, quantitative evaluations and to identify useful biomarkers and clinical outcome measures for use in future Lafora treatment studies.

Phase N/A

The Biomarkers of Neurological Disease in Utero Study

BACKGROUND There are approximately 50 million people with epilepsy worldwide, with approximately 3-5 births per thousand to women with epilepsy in the United Kingdom (UK) there are 2500 births per year to women with epilepsy. The teratogenic effects of anti-epileptic drugs (AEDs) on the fetus is a major public health ...

Phase N/A