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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (260) clinical trials

Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy

This is a phase I, two-stage, prospective, open label, single center, and single-arm study. Eligible patients will be enrolled through the process of informed consent then will receive NaviFUS treatment one cycle. The time interval for each treatment cycle is 3 days, including baseline/treatment and 3 days observation. The site ...

Phase N/A

A Pilot Study of the Low Glycaemic Index Diet in Adults With Epilepsy

Many persons with epilepsy have seizures which remain uncontrolled by anti-epilepsy medications and are unsuitable for or unwilling to undergo surgical treatments for their epilepsy, or have undergone such treatments and continue to have seizures. Dietary treatments for epilepsy have been shown to be effective in children, and are probably ...

Phase N/A

Novel Network Analysis of Intracranial Stereoelectroencephalography

Hypothesis The hypothesis is that analysis of ictal (during seizure) and interictal (between seizures) single neuronal firing dynamics will identify ictogenic tissue in children undergoing SEEG recording for focal epilepsy. Study Design Prospective cohort study. Sample Size The investigators will aim to recruit 30 patients over a period of 3 ...

Phase N/A

Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia

Focal Cortical Dysplasias (FCDs) are neurodevelopmental disorders that represent a major cause of early onset drug-resistant epilepsies with cognitive and behavioral impairments, carrying a lifelong perspective of disability and reduced quality of life. Despite a major medical and socio-economic burden, rationale therapeutic strategies are still under debate. Surgical removal of ...

Phase N/A

A Study to Assess Safety and Efficacy of Perampanel in Indian Participants as an Adjunctive Treatment in Partial Onset Seizures With or Without Secondary Generalized Seizures in Participants With Epilepsy Aged 12 Years or Older

The purpose of this study is to assess the safety of perampanel in the treatment of partial onset seizures in participants of age 12 years and older with epilepsy.

Phase N/A

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

Advances in modern anesthesiology have significantly reduced the risk of anesthesia compared to the last century, however, the level of perioperative hospital mortality of planned operations at the moment is on average about 0.5% (ISOS group, 2016). Weiser et al. (2016) estimated that more than 313 million adults worldwide are ...

Phase N/A

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure frequency in participants with pediatric epileptic syndrome (Cohort 1) and partial-onset seizures (POS) (Cohort 2).


Youth Epilepsy and Successful Self-Management Intervention

YESS! is a web-based self management program developed to enhance the motivation and skills of youth with epilepsy. This clinical trial uses a pre-test, post-test design where all consenting participants are given access to the intervention.

Phase N/A

Circulating microRNAs as Biomarkers of RESPIratory Dysfunction in Patients With Refractory epilePSY

Sudden and unexpected death in epilepsy (SUDEP) has become a major issue for patients with epilepsy and their physicians. SUDEP is a nontraumatic and non-drowning death in patients with epilepsy, unrelated to a documented status epilepticus, in which postmortem examination does not reveal a toxicologic or anatomic cause of death. ...

Phase N/A

Headache Inducing Effect of Levcromakalim in Migraine With Aura Patients

To investigate the role of KATP channels in migraine with aura patients.

Phase N/A