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Pemphigus Vulgaris (PV) Clinical Trials

A listing of Pemphigus Vulgaris (PV) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (7) clinical trials

Identification of Vulnerability Factors in the Course of Pemphigus Patients

The originality of the project lies in its multidisciplinary approach (dermatology, psychology, sociology). No such study has yet been carried out in the pemphigus who has been the subject of a very small number of works in sociology or psychology. The only studies are studies of quality of life with ...

Phase N/A

A Study of PRN1008 in Patients With Pemphigus

Approximately 120 male or female patients with newly diagnosed or relapsing moderate to severe pemphigus (pemphigus vulgaris [PV] or pemphigus foliaceus [PF]) will be enrolled in the trial worldwide. The trial will last 68 weeks (approximately 17 months) for each participant. Patients will be randomized at Day 1, using a ...

Phase

Phenotypic and Functional Characterisation of Human B-cell Response in Pemphigus

Pemphigus is a rare autoimmune disease involving skin and mucous membranes with an incidence estimated as 0.7 to 7 new cases per million per year, responsible for non-negligible morbidity and mortality. Pemphigus is characterized by the production of pathogenic autoantibodies directed against two desmosomal proteins involved in keratinocyte adhesion (i.e. ...

Phase N/A

A Study to Evaluate the Safety PD PK and Efficacy of ARGX-113 in Patients With Pemphigus

The proposed study is an open-label, non-controlled, adaptive-design Phase II study to evaluate the safety, pharmacodynamics, pharmacokinetics, efficacy, and conditions of use (dosage, frequency of administration at maintenance) of ARGX-113 in patients with mild to moderate Pemphigus Vulgaris, either newly diagnosed or relapsing. The total study duration for each patient ...

Phase

Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus

Up to 12 adults between the ages of 18 and 75 years of age who have been diagnosed with pemphigus and meet all other entry criteria will be enrolled to receive one infusion of their own expanded Tregs at one of the following doses: 1.0 x 10^8 PolyTregs or 2.5 ...

Phase

A Safety and Dose-Finding Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus)

This is a multicenter, open-label safety study to determine the dose regimen of SYNT001 administered intravenously in subjects with pemphigus (vulgaris or foliaceus).

Phase

Autoimmune Blistering Diseases Study

The disease severity instruments for pemphigus and BP, the Pemphigus Disease Area Index (PDAI) and the Bullous Pemphigoid Disease Area Index (BPDAI), respectively, have the potential to capture changes in all grades of disease activity, including mild disease, and therefore represent a substantial improvement over simple lesion counts or measurements ...

Phase N/A