Joint Injuries Clinical Trials

A listing of Joint Injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 98 clinical trials
Training Single Arm

The pulmonary hypertension is a disease, which tends to a progredient right heart failure. Although there was a large progress in development of medical therapy, the quality of life, the physical efficiency and the prognosis of the patients are still limited. The aim of the study is to examine the …

right ventricular failure
right heart catheterization
heart failure
  • 1 views
  • 10 May, 2021
  • 1 location
Effect of Exercise and Respiratory Therapy on Right Ventricular Function in Severe Pulmonary Hypertension

Chronic pulmonary hypertension (PH) is associated with impaired exercise capacity, quality of life and right ventricular function.The disease is characterized by an increase of pulmonary vascular resistance and pulmonary arterial pressure, leading to right heart insufficiency. In later stages of the disease, the right heart is not able to further …

pulmonary arterial hypertension
right heart catheterization
pulmonary arterial pressure
heart failure
  • 7 views
  • 11 May, 2021
  • 1 location
Effect of Home Rehabilitation on State of Patients With PAH HFREF and IHD

The aim of the study is to evaluate the influence of physical training and respiratory rehabilitation performed by patients at home on quality of life, symptoms, physical endurance, force of respiratory and skeletal muscles and body mass composition in patients with pulmonary arterial hypertension (PAH) or left ventricular heart failure …

rehabilitation therapy
cardiac rehabilitation
connective tissue diseases
hypertension
pulmonary arterial pressure
  • 8 views
  • 21 Feb, 2021
  • 2 locations
A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis at Risk for Pulmonary Hypertension

A randomized, double-blind, placebo-controlled dose escalation and verification study to assess the safety and efficacy of pulsed inhaled nitric oxide (iNO) in subjects at risk for pulmonary hypertension associated with pulmonary fibrosis on long term oxygen therapy (Part 1 and Part 2) - REBUILD

emphysema
endothelin receptor antagonist
dyspnea
pulmonary fibrosis
pulmonary disease
  • 168 views
  • 13 Aug, 2021
  • 55 locations
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

congenital heart defects
pulmonary arterial pressure
scleroderma
assisted ventilation
right heart catheterization
  • 10 views
  • 20 Jul, 2021
  • 9 locations
A Study of Oral Nitrate in Adults With Pulmonary Hypertension With Heart Failure and Preserved Ejection Fraction

This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in healthy adult normal volunteers compared to volunteers with PH-HFpEF in the breakdown of oral nitrate.

ejection fraction
right heart catheterization
hypertension
heart failure
heart disease
  • 21 views
  • 17 Sep, 2021
  • 2 locations
Outpatient Vasodilator Assessment Using Iloprost in Pulmonary Hypertension

This study will compare the clinical efficacy of inhaled iloprost as an invasive, selective vasodilator in the cardiac catheterization laboratory in patients with pulmonary hypertension to the gold standard of inhaled nitric oxide. It will also examine whether echocardiographic estimates of response to inhaled iloprost can predict responsiveness to invasive …

nitric oxide
vasodilator
iloprost
  • 1 views
  • 11 Jul, 2021
  • 1 location
Impedancemetry in Patients Monitored for Pulmonary Hypertension

Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension

  • 1 views
  • 26 Jan, 2021
  • 1 location
A Dose Escalation Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Fibrosis or Sarcoidosis

A phase 2b, open label study to assess the safety and efficacy of increasing doses of pulsed, inhaled nitric oxide (iNO) in subjects with pulmonary fibrosis and sarcoidosis on long term oxygen therapy followed by a long term extension study

pulmonary fibrosis
pulmonary disease
pulmonary arterial pressure
nitric oxide
fibrosis
  • 171 views
  • 13 May, 2021
  • 6 locations
Development of Novel Physiological CMR Methods in Health and Disease

Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them offer varied insight into cardiac physiological adaptation: passive leg raise, intra-venous fluid challenge, pharmacological stressors and physical exercise stress test. …

exercise stress test
heart disease
  • 34 views
  • 15 Jul, 2021
  • 1 location