Urethral Strictures Clinical Trials

A listing of Urethral Strictures medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 18 clinical trials
Featured trial
A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

A multicenter clinical study of the Sonablate® 500 (Sonablate) for the TreAtment of locally Recurrent prostate cancer with HIFU(STAR Trial)

  • 25 Mar, 2021
  • 1 location
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures. (VeSpAR)

The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of

  • 23 Apr, 2022
  • 4 locations
DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures (DoVe)

For bulbar urethral strictures, it remains unclear whether ventral onlay graft urethroplasty is non-inferior to dorsal onlay graft urethroplasty in terms of patency rates.

  • 22 Mar, 2022
  • 1 location
Multi-stage Urethroplasty With Augmentation Using a Dorsal Graft Inlay Technique Comparing Graft Use in First or Second Stage

The principal aim of this pilot study is to directly compare both approaches and analyze the failure rate after one year of follow-up. These data will serve as the basis to design a larger phase II or III trial in the future with failure rate as the primary end-point. Other …

  • 25 Jul, 2021
  • 1 location
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters (STREAM)

Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 55 years of age.

  • 04 Jun, 2022
  • 1 location
Clostridium Histolyticum Collagenase Injection for Urethral Disease

The purpose of this study is to assess the efficacy of clostridium histolyticum collagenase (XIAFLEX®) in treating urethral strictures.

  • 09 Jun, 2022
  • 1 location
Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures

In this study the investigators investigate the feasibility and therapeutic potential of free autologous fat grafting combined to direct visual urethrotomy (DVIU) in the treatment of urethral

  • 04 Jun, 2021
  • 1 location
Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty

The investigator's study aims to see if an enhanced recovery regimen of pain medications before and during surgery will decrease the use and risk of opioid pain medications as well as improve pain control in anterior urethroplasty patients. Participants will be randomized to one of two pain regimens (enhanced recovery …

ibuprofen 800 mg
  • 07 Feb, 2022
  • 1 location
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty (Buccal)

Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this …

  • 19 Apr, 2022
  • 1 location
ProACT Post-Approval Study

The ProACT Post Approval Study is a 5-year prospective, open-label, multi-center study designed to evaluate the long-term incidence of urethral stricture and device erosion after ProACT

Accepts healthy volunteers
urethral stricture
  • 29 Apr, 2022
  • 3 locations