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Diabetes Mellitus, Type 2 Clinical Trials

A listing of Diabetes Mellitus, Type 2 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (187) clinical trials

Epigenetic Contribution to the Pathogenesis of Diabetic Nephropathy in Qatari Population

Diabetic nephropathy (DN) is a common vascular complication of Type 2 diabetes (T2D) that is associated with increased mortality and poor quality of life.In industrialized countries, DN ranges first among other etiologies of end-stage renal disease (ESRD).Diabetes in Qatar is a serious health issue for the Qatari population since approximately ...

Phase N/A

Microvascular Blood Flow and Metabolic Flexibility in Hispanics

Metabolic disease, including type 2 diabetes (T2D) and pre-diabetes is a significant health issue globally, particularly in the Hispanic population. The impact of this disease on morbidity and mortality is unquestionable, as it is associated with various aspects of neural and cardiovascular disease. The incidence of T2D is continually increasing, ...

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Mitigation of Type 2 Diabetes by Partial Ileal Bypass

The partial ileal bypass (PIB) operation is a standard procedure used in the management of hyperlipidmia since 1963. POSCH was the intervention modality in the National Institutes of Health, National Heart Lung and Blood Institute-funded Program on the Surgical Control of the Hyperlipidemias (POSCH) trial. The POSCH study was a ...

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The Sapienza University Mortality and Morbidity Events Rate (SUMMER) Study in Diabetes

Background Mortality rate of diabetic patients is about twice as much that of non-diabetic individuals of similar age; this makes diabetes a leading risk factor for mortality, especially of cardiovascular origin, which accounts for 2.9 million global events yearly. Such scenario is expected to further deteriorate, given that the prevalence ...

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Pathways for Health Equity Quality Improvement Strategy

GOAL To improve the health and health equity of Indigenous peoples by strengthening the effectiveness, sustainability and scalability of a promising community-driven and culturally-relevant quality improvement strategy through meaningful conversations and engagement with our community partners. OBJECTIVES Engage community partners and key stakeholders to support meaningful participation and leadership Review, ...

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DNA Methylation and Gene Expression in Qataris With Type 2 Diabetes

The global prevalence of Type 2 Diabetes (T2D) is rapidly rising throughout most regions of the developed and developing world. In Middle East countries, particularly in the Gulf Council countries, the diabetes pandemic along with the rates of obesity have risen due to the adoption of a modern lifestyle. In ...

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Evaluating for Type-2 Diabetes in the Very Early Postpartum Period

This will be a prospective cohort study conducted at Winthrop-University Hospital. Women 18 years old or older who delivered a child or fetus within the previous 4 days at either hospital who also were diagnosed with GDM during the pregnancy will be eligible for participation. Women will be excluded if ...

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Genetic Contribution to the Pathophysiology of the Charcot Foot in Qatari Patients With Diabetes

Diabetes is a serious health issue for the Qatari population since approximately 1/5 of the population has Type 2 Diabetes, which is 2-3 times higher than the world average. Although much of the clinical studies of diabetes often focused on microvascular phenotypes such as retinopathy and nephropathy, and macrovascular diseases ...

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Early MRI Detection of Myocardial Deterioration as a Preventive Disease Staging and Prognostic Biomarker in Insulin Resistance

Cardiac fibrosis has been linked to adverse outcomes in non-ischemic cardiomyopathy. Fibrosis is also detectable in diabetic patients, but does not appear to closely track with insulin sensitivity. Hence, fibrosis may be an independent risk factor for adverse outcomes in IR and diabetic patients. As a result, a critical need ...

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Shift Work Heredity Insulin and Food Timing Study

Preliminary observations suggest that food intake coincident with high melatonin levels leads to impaired glucose toleranceparticularly in MTNR1B risk allele carriers. Our objectives are to determine the effect of concurrent food intake and melatonin on glucose tolerance; and to assess the role of MTNR1B single nucleotide polymorphism (SNP)*melatonin interaction in ...

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