Nerve Injury Clinical Trials

A listing of Nerve Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 55 clinical trials
Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study (COPS)

Nerve injury in the fingers is a common injury and affects people of all ages. The treatment usually offered to patients is surgery and various types of rehabilitation. There is a lack of

  • 07 Oct, 2022
  • 1 location
Condylar Head Operative or Conservative 1, Randomised Controlled Trial (CHOC1)

The condylar head is the part of the lower jaw which forms the joint. Displaced fractures of this area are uncommon but can cause problems with function, such as chewing, if not treated effectively. The medical literature does not have a clear consensus on whether these should be treated operatively …

Accepts healthy volunteers
  • 17 Oct, 2022
  • 1 location
Evaluation the Efficiency of Intravenous Dexmedetomidine Under Nasal Humidification Rapid Ventilation Device Without Intubation in Laryngoscope Microsurgery

Method This single-center randomized-controlled trial is conducted to compare the efficiency of LMS with intubated general anesthesia(ITGA) and LMS with nonintubated anesthesia. The study also performed a comparative evaluation of the safety and feasibility of LMS with nonintubated general anesthesia under two different ventilation strategies. The investigators plan to enroll …

  • 22 Oct, 2022
  • 1 location
A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-Controlled, Adaptive Design Study to Evaluate the Efficacy and Safety of MK-5475 in Adults With Pulmonary Arterial Hypertension

This is a two-part (Phase 2/Phase 3) study of MK-5475, an inhaled soluble guanylate cyclase stimulator, in participants with pulmonary arterial hypertension (PAH). The first part (Phase 2) will assess three different doses of MK-5475 compared to placebo in a base period of 12 weeks, followed by comparison of three …

right heart catheterization
body mass index
pulmonary arterial hypertension
heart disease
left ventricular end-diastolic pressure
  • 20 Oct, 2022
  • 76 locations
The Prophet Trial -Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension (AFR-Prophet)

This study aims to investigate safety and efficacy of Occlutech® AFR device in patients with severe pulmonary hypertension (PH).

pulmonary arterial pressure
right ventricular failure
heart failure
  • 07 Oct, 2022
  • 12 locations
A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group, Event-Driven, Group-Sequential Study With Open-Label Extension Period to Assess the Efficacy and Safety of Selexipag as Add-On Treatment to Standard of Care in Children Aged >=2 to <18 Years With Pulmonary Arterial Hypertension (SALTO)

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.

right heart catheterization
endothelin receptor antagonist
primary pulmonary hypertension
pulmonary arterial hypertension
heart disease
  • 25 Oct, 2022
  • 84 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH (CAPACITY)

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

exercise stress test
cardiopulmonary exercise testing
endothelin receptor antagonist
stress test
  • 04 Oct, 2022
  • 36 locations
PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2 (PERK2)

PrEvention of posttraumatic contractuRes with Ketotifen 2 (PERK 2) is a Phase III randomized, controlled, double blinded multicenter trial with 3 parallel groups (Ketotifen 2 mg or 5 mg or lactose placebo twice daily orally for 6 weeks) and a primary endpoint of elbow extension-flexion range of motion (ROM) arc …

  • 16 Oct, 2022
  • 15 locations
STaR (Surgical Timing and Rehabilitation) Trial for Multiple Ligament Knee Injuries

The purpose of this study is to investigate effects of timing of surgery (early vs. delayed) and timing of post-operative rehabilitation (early vs. delayed) for the treatment of military personnel and civilians that sustain a multiple ligament knee injury. To achieve this overall objective of this project, we will conduct …

  • 15 Oct, 2022
  • 1 location
Electrical Stimulation to Enhance Peripheral Nerve Regeneration

injury. Injuries causing nerve damage in the arm and hand are common. In severe cases, functional outcomes even with surgery remain poor. Recently, electrical stimulation has been applied to injured

nerve damage
nerve conduction studies
nerve conduction
  • 04 Oct, 2022
  • 1 location