Endometriosis Clinical Trials

A listing of Endometriosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 168 clinical trials
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery

Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience of surgeons. The identification of nerves is often needed in gynecological surgery, such as the obturator nerves in …

ovarian cancer
lymphadenectomy
sarcoma
endometriosis
uterine myomatosis
  • 5 views
  • 24 Feb, 2022
  • 1 location
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States. Here, the investigators plan to conduct a randomized, double-blinded, placebo-controlled clinical trial to 1) compare the efficacy of peripheral (lidocaine/estradiol cream), centrally-targeted …

nortriptyline
estradiol
vulvar pain
sham treatment
antidepressant
  • 546 views
  • 14 Feb, 2022
  • 2 locations
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction (MUSIC-HFrEF1)

It is believed that targeted SERCA2a enzyme replacement in HFrEF patients will correct defective intracellular Ca2+ hemostasis, resulting in improved cardiac contractile function and energetics which will, in turn, translate to improved clinical outcomes. Additionally, it is hypothesized that correcting SERCA2a dysfunction will also improve coronary blood flow through correction …

calcium
ejection fraction
cardiomyopathy
heart failure
  • 0 views
  • 04 Oct, 2022
  • 1 location
The LUCINDA Trial: LeUprolide Plus Cholinesterase Inhibition to Reduce Neurological Decline in Alzheimer's (LUCINDA)

The LUCINDA Trial is a three-site, phase II, randomized, double-blind, placebo-controlled study of leuprolide acetate (Eligard) in women with Mild Cognitive Impairment or Alzheimer's Disease taking a stable dose of donepezil (Aricept.) Its objective is to assess the efficacy of a 48-week regimen of leuprolide (22.5 mg per 12 weeks) …

cholinesterase
memantine
mild cognitive impairment
dementia
mini-mental state examination
  • 49 views
  • 04 Oct, 2022
  • 1 location
Phase I Trial of Defatcinib and VS-6766. (FRAME)

This is a multi-centre, investigator-initiated, dose escalation, Phase I trial of the combination of the FAK inhibitor, Defactinib (VS-6063), and the dual RAF/MEK inhibitor, VS-6766 (RO5126766) in patients with advanced solid tumours. VS-6766 (RO5126766) is the same compound as CH5126766. There are two parts to this study, the dose escalation …

KRAS
x-rays
measurable disease
lung carcinoma
neutrophil count
  • 15 views
  • 27 Apr, 2022
  • 5 locations
Pain Relief in Laparoscopic Surgery

Pain relief after laparoscopic surgery with the use of an altered gas.

pain relief
hysterectomy
laparoscopic surgery
  • 0 views
  • 27 Feb, 2022
  • 1 location
Arrhythmogenic Substrate in Primary Cardiomyopathies and/or Channellopathies

This study assesses the value of arrhythmogenic substrate identification and elimination by catheter ablation to prevent recurrent ventricular arrhythmias and sudden cardiac death in a series of selected patients with primary cardiomyopathy and/or channellopaties with ICD implantation.

cardiomyopathy
arrhythmia
catheter ablation
sudden cardiac death
fibrillation
  • 21 views
  • 08 May, 2021
  • 1 location
New MRI Methods Applied to Heart Failure With Preserved Ejection Fraction (HFpEF)

This study's main specific aims are; To develop robust acquisition and reconstruction methods specifically for the study of microvascular cardiac remodeling with MRI which will include very innovative quantitative perfusion methods, as well as fibrosis quantification, longitudinal strain, and phase contrast imaging for flow. Test the new methods for identifying …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Efficacy of an Endoluminal-suturing Device (Endomina) on Severe Obstructive Sleep Apnea Syndrome : EndoSAS (EndoSAS)

This study aims to evaluate the efficacy of an endoluminal gastric plication using an endoluminal-suturing device to improve severe OSAS in patients with a BMI above or equal to 28 kg/m² until 34.9kg/m².

obstructive sleep apnea
  • 0 views
  • 15 Oct, 2022
  • 1 location
Investigation of Non-Invasive Pulsed Electromagnetic Field (PEMF) Therapy for Female Patients With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy. The study team will distribute the PEMF device to female adults with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) to measure its ability to …

  • 0 views
  • 12 Oct, 2022
  • 1 location